Lorrca
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Catalog excerpts

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The analysis of the rheology (flowing capacity) of red blood cells is a very specific task. It is vital in the research of some very serious diseases like sickle cell disease, malaria, diabetes, hereditary blood disorders, and other abnormalities that are linked to red blood cells. In close collaboration with our science and technology partners, RR Mechatronics has developed the Lorrca: an ektacytometer with added capabilities. Scientists in over 20 countries use the Lorrca to contribute to research, often in research environments. The Lorrca is also used clinically, especially in the field...

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Applications Deformability is a measure of the RBC’s condition. It is a good indicator of the blood quality at blood banks but can also indicate future organ failure, among others in diabetics, and allows for the assessment of oxidative stress-related complications. Sickle cells blocking blood flow Sticky sickle cells How Does the Lorrca Work? To evaluate the rheology of blood in different parts of the body it is important to have a technique available that can accurately measure RBC properties such as deformability, stability, and aggregation. The Lorrca incorporates a variety of...

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Aggregation v=au) 0 Ttop Shape recovery stage Disaggregation stage How is it measured? The rouleaux formation is revealed by measuring the change in light absorption following a sudden stop in the applied shear stress on the RBC’s. The rouleaux dispersion threshold value is measured by varying the shear stress until rouleaux formation is only just prevented. This point is marked by the lowest possible amount of light reflection. What does it measure? The Lorrca measures the speed at which rouleaux formation occurs and the minimal shear force at which rouleaux remain dispersed. Other...

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Our Customers The Lorrca is of great use for hematologists at large laboratories, blood banks, pharmaceutical companies and contract research organizations, scientific research institutes specialized in blood rheology, for research on sickle cell disease and malaria, for oxidative stress related research and so on. The Lorrca is a versatile small footprint instrument that fits on every desk. Social Responsibility The unique collaboration between the scientific world and our R&D department enabled us to develop the Lorrca. The medical world regards the technique used by the Lorrca to be the...

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Mechatronics Instruments B.V. De Corantijn 13, 1689 AN Zwaag, The Netherlands P.O. Box 225, 1620 AE Hoorn, The Netherlands T + 31 229 291 129 sales@rrmechatronics.com www.rrmechatronics.com Mechatronics USA LLC 20 Altieri Way, Unit 4 Warwick, RI 02886 USA T + 1 401 431-6101 salesamericas@rrmechatronics.com www.rrmechatronics.com

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