Cardiology and Lipid Testing LT147 - 28 Pages

  1. P. 1

  2. P. 2

  3. P. 3

  4. P. 4

  5. P. 5

  6. P. 6

  7. P. 7

  8. P. 8

  9. P. 9

  10. P. 10

  11. P. 20

Catalogue excerpts

COMPLETE CARDIOLOGY AND LIPID TESTING FROM RANDOX CARDIOLOGY & LIPID TESTING

 Open the catalogue to page 1

18 - 19 Heart-type Fatty Acid Binding Protein (H-FABP) 20 CK-MB 20 Myoglobin RISK ASSESSMENT MONITORING 04 - 05 HDL Cholesterol 06 - 07 LDL Cholesterol 08 Cholesterol 08 Triglycerides 09 sLDL Cholesterol 10 - 11 Lipoprotein (a) 12 Apolipoprotein A-I 12 Apolipoprotein B 12 Apolipoprotein A-II 13 Apolipoprotein C-II 13 Apolipoprotein C-III 13 Apolipoprotein E 14 HDL3-C 15 sPLA2-IIA 16 Homocysteine 16 High Sensitivity CRP 17 Adiponectin 24 - 25 Ordering Information 26 References THERAPY MONITORING UNIQUE FEATURE When you see this symbol you will know that this feature is unique to the Randox product NICHE...

 Open the catalogue to page 2

INTRODUCTION TO RANDOX CARDIOLOGY AND LIPID TESTING The need for a more extensive lipid profiling is on the increase, to truly identify the risk of cardiovascular diseases, both in primary and secondary risk categories; and as such provide the necessary tools to prevent and reduce the risks. Randox offer a comprehensive cardiology product profile which includes high performance reagents for the detection of conventional risk factors, as well as emerging biomarkers associated with further risk. BELOW THE AGE OF 70, CVDs ARE RESPONSIBLE FOR 39% OF ALL NCD DEATHS. - World Heart Federation, 2017 Please...

 Open the catalogue to page 3

HDL CHOLESTEROL Clinical Significance Key Features of Randox HDL Cholesterol • UF • • • Superior direct clearance methodology - ensuring truly accurate results even with abnormal samples Liquid ready-to-use reagents - for convenience and ease of use Extensive measuring range - of 0.189 - 3.73mmol/l for measurement of clinically important results Applications available for an extensive range of biochemistry analysers - which detail instrument-specific settings for the convenient use of Randox HDL Cholesterol assays on a variety of systems High-density lipoproteins (HDL) are one of the major classes...

 Open the catalogue to page 4

Fig, 2 Specificity of Randox Direct Clearance Assay for HDL Cholesterol Specifi city of the Randox direct clearance HDL assay was verified against gel filtration. Fig. 2 shows just how specific the Randox direct clearance method is for HDL Cholesterol. Our kit was found to only react with the HDL fractions separated by gel filtration. Total Cholesterol Reagent Randox HDL Cholesterol Reagent THE DIAGRAM ABOVE SHOWS HOW SPECIFIC THE RANDOX DIRECT CLEARANCE METHOD IS All ordering information can be found on Page 24-25

 Open the catalogue to page 5

LDL CHOLESTEROL Excellent precision - Our LDL assay retains its precision even at high levels of triglycerides. Key Features of Randox LDL Cholesterol • • • • UF Superior direct clearance methodology - ensuring truly accurate results are delivered Liquid ready-to-use reagents - convenience and ease-of-use Extensive measuring range - of 0.189 – 22.2mmol/l for measurement of clinically important results Applications available for an extensive range of biochemistry analysers which detail instrument-specific settings for the convenient use of Randox LDL Cholesterol assays on a variety of systems Benefits...

 Open the catalogue to page 6

VLDL LDL HDL Fig. 4 Specificity of Randox Direct Clearance Assay for LDL Cholesterol Specificity of the Randox direct clearance LDL assay was verified against gel filtration. Fig. 4 shows just how specific the Randox direct clearance method is for LDL Cholesterol. Our kit was found to only react with the LDL fractions separated by gel filtration. Total Cholesterol FORMULA HAS BEEN REPORTED TO MISCLASSIFY UP TO 50% OF PATIENTS2 All ordering information can be found on Page 24-25

 Open the catalogue to page 7

Triglycerides: recommended levels below 1.7 mmol/l Cholesterol: recommended levels below CHOLESTEROL (TOTAL) Key Features of Randox Cholesterol • Wide range of kits available - ensuring laboratories of all sizes can fi nd a product to suit their needs • Liquid ready-to-use reagents - for convenience and ease-of-use • Standards included in manual kits - for user convenience (these are for manual and semi-automated use only) • Extensive measuring range - of 0.865-16.6 mmol/l for measurement of clinically important results • Applications available for an extensive range of biochemistry analysers...

 Open the catalogue to page 8

SMALL-DENSE LDL (sLDL) CHOLESTEROL Fig. 5 Correlation of Ultracentrifugation and Seiken Methods5 Until recently, the primary methods of assessing a patient’s sLDL were based on techniques such as ultracentrifugation and electrophoresis both of which are extremely laborious and time-consuming. 3 sLDL can now be assessed in the routine biochemistry laboratory using the Randox immunoturbidimetric assay. • Randox sLDL utilises the “Denka Seiken” method - which produces results in ten minutes. There are two main reaction steps based on the presence of surfactants and enzymes that selectively react...

 Open the catalogue to page 9

Criteria to overcome challenges of Lp(a) measurement Traditional challenges of Lp(a) measurement The widespread use of Lp(a) as an independent risk factor for cardiovascular disease risk has, until recently, been impeded by the lack of internationally accepted standardisation and the fact that many commercial Lp(a) methods suffer from apo(a) size related bias, potentially leading to patient misclassification. The size heterogeneity of apo(a) affects to varying degrees the results of many commercially available Lp(a) kits. This may result in an underestimation of Lp(a) in samples containing apo(a)...

 Open the catalogue to page 10

Clinical Significance The size of the apo(a) protein is genetically determined and varies widely hence, levels of Lp(a) can vary up to 1000-fold between individuals.7 Recent years have seen major scientific advances in the understanding of Lp(a) and its causal role in premature CVD. Elevated Lp(a) levels associate robustly and specifically with increased CVD risk. Additional Risks • Along with other tests, Lp(a) can provide additional information on a patient’s risk factor of developing cardiovascular disease • It is particulary useful for determining the risk of cardiovascular disease (CVD) in...

 Open the catalogue to page 11

All Randox Laboratories catalogues and technical brochures

  1. RX modena

    22 Pages

    En
  2. RX Series

    13 Pages

    En
  3. Linearity sets

    16 Pages

    En
  4. 2017 Product List

    92 Pages

    En
  5. Evidence

    16 Pages

    En
  6. Acusera 24•7

    20 Pages

    En
  7. Acusera

    132 Pages

    En
  8. Evidence Evolution

    16 Pages

    En
  9. RX Monaco

    16 Pages

    En
  10. Rx Imola

    16 Pages

    En
  11. RX Daytona Plus

    16 Pages

    En
  12. Rx Monza

    16 Pages

    En
  13. Carbon Dioxide

    2 Pages

    En
  14. Thyroid Arrays

    4 Pages

    En
  15. Cerebral Arrays

    4 Pages

    En
  16. Endocrine Array

    4 Pages

    En
  17. Rx Daytona

    16 Pages

    En

Archived catalogues

  1. RIQAS Explained

    36 Pages

    En
  2. Molecular Testing

    16 Pages

    En
  3. Fertility Array

    4 Pages

    En
  4. Evidence

    16 Pages

    En