Cerebral Arrays - 4 Pages

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Catalogue excerpts

Cerebral Arrays Rapid and accurate testing of analytes related to nervous system dysfunction

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Cerebral arrays For the simultaneous measurement of analytes associated with nervous system dysfunction Randox Cerebral arrays are designed for the simultaneous measurement of analytes associated with nervous system dysfunctions such as cerebrovascular disease, Alzheimer’s disease and Multiple Sclerosis (MS). Key Benefits • easures up to five biomarkers simultaneously M • Simple sample preparation • Human serum, plasma and cerebrospinal fluid (CSF) samples • Wide measuring range • Small sample volume, just 35 - 100µl • Fast throughput • or use with fully and semi-automated analysers F • Excellent...

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Brain-Derived Neurotrophic Factor (BDNF) C-reactive protein (CRP) – Fastest acting acute phase A neurotrophin; widely distributed throughout the central nervous system. It limits neurodegenerative damage after brain injury and is a good marker for stroke detection. protein. While high levels indicate infection/inflammation, mildly increased levels are associated with cardiovascular disease. Glial Fibrillary Acidic Protein (GFAP) – Specific marker D-dimer – Mediates both clot formation and fibrinolysis. for astrocyte damage. It is significantly elevated following stroke onset. The release pattern...

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Examples of Research Applications for Cerebral Arrays Cerebral Arrays have been used in a number of studies with independent publications shown in the table below. Condition Research Application Amateur boxers Observational case-control study. Measurement of analytes in serum. Zetterberg, H. et al. (2009) Brain Injury 23: 723-726 Down syndrome Investigation of the relationship between age and BDNF levels in Down syndrome. Dogliotti, G. et al. (2010) Immunity & Ageing 7: 2 Alzheimer’s disease, vascular dementia, frontotemporal dementia, dementia with Lewy bodies, mild cognitive impairment. Measurement...

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