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QUASAR™ Dynamic Contrast Enhanced C - 1

Calibrate Dynamic Contrast Enhanced CT measurements for cross platform comparisons STANDARDIZE DYNAMIC CONTRAST ENHANCED CT MEASUREMENTS Dynamic Contrast Enhanced CT (DCE-CT) is increasingly evaluated for treatment response assessment and is routinely used for cancer imaging and staging. Contrast agent (Iodine) injections lead to a large range of density values in vessels of different size and orientation. These variables, although important, are not fully tested with current QA techniques. The DCE-CT system, consisting of a phantom and automated image analysis software, is the only comprehensive product available in the market to quantify and calibrate the CT number linearity for densities applicable to iodine injections. This makes possible the quantification of DCE-CT values independent of scan parameters (mAs, kV), machine, manufacturer, and DCE software. The system is designed with daily, monthly, and annual CT calibration of DCE-CT measurements in mind. ± Quantify sensitivity and accuracy of DCE-CT measurements ± Compare DCE-CT results from multiple vendors ± Contrast multi-institutional studies ± Analyze multiple vessel diameters and orientations ± Verify motion induced changes in DCE-CT measurements ± Calibrate your scanner daily, monthly and annually ± Automated image analysis software included with phantom Automated image analysis software is used to determine volume definition, spatial resolution, and MTF. The software plots the change in CT number vs vessel size and orientation for calibration of DCE-CT measurements. It is compatible with all recent Windows operating systems including the latest Windows 8. The DCE-CT phantom contains capsules of different diameter (1, 2, 5, and 10 mm) and orientation (0˚, 45˚, and 90˚) to mimic the diversity of blood vessels in the body. The capsules are solid materials of different densities used to model different concentrations of iodine contrast agents. No liquid solutions are required; therefore, no evaporation will occur providing a stable phantom for long term reproducible QA. An optional motion platform is available to quantify the effect of motion on DCE-CT acquisitions. Accuracy. Confidence. Specifications subject to change without notice. Modus Medical Devices Inc is not responsible for errors or omissions. All rights reserved. ©2014 Modus Medical Devices Inc. PDS100-1019

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QUASAR™ Dynamic Contrast Enhanced C - 2

Accuracy. Confidence. Quality Assurance System for Advanced Radiology and Radiotherapy (QUASAR™) Modus offers a range of cost-effective and innovative quality assurance tools for imaging, image guidance and radiotherapy. QUASAR™ tools are a valuable part of any quality assurance program. Designed by and for medical physicists, QUASAR™ quality assurance tools provide you with confidence that every patient is getting the best possible care. Calibrate Dynamic Contrast Enhanced CT measurements for cross platform comparisons PRODUCT SPECIFICATIONS ± Phantom constructed of acrylic with capsules...

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