Spiral Gradient Endpoint? (SGE?) Test
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SGE™ SPIRAL GRADIENT ENDPOINT TEST FOR ANTIMICROBIAL SUSCEPTIBILITY DETERMINATIONS Multiple Uses for Antimicrobial Testing committed to bringing you innovative products to improve laboratory productivity, while saving time and materials. The newly updated Windows® based SGE software, with expanded features, is another example established, published, technique with a growing presence in drug discovery and agricultural pesticide applications. Created by the company that pioneered automated microbiology systems nearly 30 years ago, and guided by microbiolo- gists, Advanced Instruments, Inc. recognizes your need for proficient customer service and technical support teams. Quality is the most important feature we build into our products. An antimicrobial compound is spiral plated onto an agar plate and up to 15 microbial suspensions per plate are swabbed radially across the gradient. precise concentration of compound at the endpoint of growth for each microbe. This technique removes the limits of two-fold values used with conventional tests and saves time and materials (one SGE plate equals 8 two-fold dilution plates). Drug Discovery SGE plates can be prepared with your compounds, not just those commercially available, making it a valuable screening tool Synergy Testing The SGE software calculates stock concentrations to plate in order to place the endpoint of growth at a specific location. When two compounds are applied to the same plate, this feature allows determination of antagonistic and synergistic effects. In addition, one compound can be applied uniformly, while the other varies exponentially Resistance Development Resistant "outlier" colonies may be present past the endpoint of growth study. Reculturing and testing of these colonies through serial passage techniques can indicate the likelihood SGE™ FROM ADVANCED INSTRUMENTS, INC.

SGE™ SPIRAL GRADIENT ENDPOINT TEST Intuitive Windows® Based Interface Draws plate images as Saves user-defined stock concentrations Standard Autoplate® and Model D Spiral Platers in exponential and uniform modes Calculates precise two-fold equivalents System Requirements Operating Systems: Windows 95 or higher AGP (Video Card) Slot: 8MB RAM or higher Monitor: 17" viewable area, capable of 1024 x 768 or Hard Drive: 5 gigabytes or higher