Mastering the measurement of Feno – Non-invasive measurement of airway inflammation Nitric Oxide Monitoring System

NIOX® Flex – Nitric Oxide Monitoring System Easy to use – suitable for ages 4 and up CE marked and FDA cleared for clinical use4, 5 Immediate, accurate and reproducible results7 Turnkey system for non-invasive measurements C ompliant with ATS/ERS guidelines3 International gold standard User-friendly operation with visual feedback S elf test for system reliability P atient database management and easy data transfer through USB T echnical expertise provided by an experienced customer support team A number of research kits available

Casting new light on airway inflammation he NIOX® Flex Nitric Oxide Monitoring System offers a unique tool for improving the diagnosis and management of asthma through the measurement of Fractional Exhaled Nitric Oxide – Feno. NIOX Flex is the successor of NIOX, the established market leader, which, according to opinion surveys, has been globally recognized as the gold standard by researchers and clinical physicians. NIOX Flex is the result of years of extensive research and development by Aerocrine. The founders of Aerocrine were the first to determine the presence of nitric oxide (NO) in exhaled...

Chemiluminescence. NIOX® Flex uses the high sensitivity and high specificity of a chemiluminescence gas analyzer, the most accurate method available for measuring NO molecules at very low concentrations. NO-free air (scrubbed inhalation air) eliminates contamination from high ambient nitric oxide (NO) levels as stated in the ATS/ ERS guidelines. Patient dead space is exhaled unrestricted, without flow regulation to assure correct Feno result. Visual aid for the patient. Exhalation pressure may vary between 10 and 20 cm H2O without affecting flow. Unique dynamic NIOX Flow Control keeps exhalation...

Instructions Automatic Self Test between patient measurements validates the calibration and detects any zero-point drift in order to ensure that every Feno value is accurate and reproducible. Default Test Settings ensure that collected measurements comply with ATS/ERS guidelines and that the exhalation quality is assured. 1. xhale: While seated, the patient E exhales. 2. nhale NO-free air: Using the I mouthpiece, the patient inhales NO-free air to total lung capacity. This eliminates any contamination from high ambient NO levels. Automatic Maintenance Guide. A reminder indicates when to perform...

Nitric Oxide Monitoring System Want to know more about Feno measurement? Nearly 1,500 clinical papers related to the use of Feno measurement in exhaled breath have been published in peer-reviewed journals; Visit www.aerocrine.com, and select Feno in Clinical Practice to view the abstracts. For a more detailed review of available literature about exhaled NO in asthma, please refer to the annually updated Scientific Backgrounder published by Aerocrine. 510(k) K021133 References 1. Gustafsson LE, Leone AM, Persson MG, Wiklund NP, Moncada S. Endogenous nitric oxide is present in the exhaled air of...