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AGAPPE LIPIDS

AGAPPE LIPIDS

AGAPPE LIPIDS

Product catalog summary
Introduction
The document discusses the importance of lipid profiles in assessing the risk of coronary heart disease. Lipid profiles include tests for cholesterol, triglycerides, HDL, and LDL, which are indicators of potential heart attacks or strokes due to atherosclerosis. Agappe's AGLipids offers a comprehensive diagnostic solution for cardiovascular disease risk assessment.

Standard and Extended Lipid Profiles
The standard lipid profile includes cholesterol, triglycerides, HDL, and LDL. The extended profile adds Apo A1 and Apo B, with emerging risk factors like CRP ultra and Lipoprotein(a). Total cholesterol alone is insufficient for cardiac risk assessment; HDL and LDL levels are crucial.

Cholesterol Testing
Cholesterol is vital for cell building, nerve insulation, and hormone production. Excess cholesterol can lead to atherosclerosis. Agappe uses the CHOD-PAP methodology with PIPES Buffer for accurate results, offering a measuring range of 3 - 600 mg/dL.

Triglycerides Testing
Triglycerides are energy sources stored in tissues and plasma. High levels can cause atherosclerosis. Agappe employs the GPO-TOPS method for stable and accurate results, with a measuring range of 2 - 1000 mg/dL.

HDL Testing
HDL, or "good cholesterol," reduces coronary artery disease risk. Agappe uses a selective inhibition method for precise HDL detection, with a measuring range of 1 - 150 mg/dL.

LDL Testing
LDL, or "bad cholesterol," is a key factor in atherosclerosis. Direct measurement is recommended for accurate cardiac risk classification. Agappe's method offers high specificity and a measuring range of 1 - 700 mg/dL.

Apolipoproteins Testing
Apo A1 and Apo B are components of HDL and LDL, respectively, and are important for cardiovascular risk prediction. Agappe uses turbidimetric immunoassay methods with wide measuring ranges.

Lipoprotein(a) and CRP Ultra
Lipoprotein(a) is a genetic risk factor for coronary heart disease. CRP Ultra is a sensitive marker for cardiovascular disease risk, detecting low levels of inflammation.

Conclusion
Agappe Diagnostics provides reliable lipid testing solutions with advanced methodologies and high accuracy, supporting comprehensive cardiovascular risk assessment.
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Catalog excerpts

AGAPPE LIPIDS-1

Beyond Just TESTING

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AGAPPE LIPIDS-2

The Dependable Lipids Introduction The lipid profile is a group of tests that are often ordered together to determine risk of coronary heart disease. They are tests that have been shown to be good indicators of whether someone is likely to have a heart attack or stroke caused by blockage of blood vessels or hardening of the arteries -atherosclerosis. • 100% Accuracy • Greater linearity with limited interference • Advanced lipid clearing factor • High Compatibility Agappe's AGLipids includes: STANDARD LIPID PROFILE: Cholesterol, Triglycerides, HDL, LDL EXTENDED LIPID PROFILE: Apo A1 & Apo B EMERGING...

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AGAPPE LIPIDS-3

Cholesterol Cholesterol helps our body to build new cells, insulate nerves and produce hormones. When there is too much cholesterol in blood, it builds up in the walls of arteries, causing a process called atherosclerosis, a form of heart disease. • Time tested CHOD-PAP Methodology • Uses 1st grade stable PIPES Buffer for optimal enzymatic reaction for accurate results • PIPES Buffer inhibits Cholesterol like substances interfering in the reaction which offers better accuracy • Lipid clearing factor(LCF), limited interference by Triglycerides • High enzyme concentration offers linearity of600...

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AGAPPE LIPIDS-4

The Dependable Lipids AGHDL High density lipoprotein (HDL) transports cholesterol from the tissues to the liver so cholesterol can be eliminated in the bile, therefore HDL is considered to be a Good Cholesterol, the higher the HDL level lower the risk of Coronary Artery Disease. • Selective Inhibition method (with out Mg+) - The most specific method to detect HDL directly • Uses electrostatic interaction of Polyanions & Cationic compounds ensures 100% accuracy than the methods using antibodies, detergents, PEG, Enzymes, MgCl2 etc • AGHDL can detect not only normal HDL-C, but FC rich HDL or ApoE...

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AGAPPE LIPIDS-5

AGLDL LDL also known as Bad cholesterol, has become an important tool used to assess an individual's risk for developing Coronary Heart Disease. LDL acts as a key factor in the pathogenesis of atherosclerosis and is responsible for 70% of Heart diseases. Studies proved that upto 50% misclassification of patient happened by using Friedewald equation. • NCEP ATP III recommends that LDL should be directly measured for correct cardiac risk classification • Friedewald equation underestimate LDL, when TGL levels are >150 mg/dL, when chylomicrons are present, if the patient is with diabetes, coronary...

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AGAPPE LIPIDS-6

The Dependable Lipids Apo A1 It is a component of HDL particles and is often used as a biomarker for prediction of cardiovascular diseases. This test is important especially a person has low level of high-density lipoprotein (HDL-C). The genetic variants of the Apolipoproteins can have a marked effect on cardiovascular risk and are linked with familial lipoprotein disorders such as hypertriglyceridaemia. • Turbidimetric Immuno assay method • Ready to use reagents • Wide measuring range • No Prozone effect up to 5500 mg/dL • Calibrator provided for Multipoint calibration • Excellent correlation...

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AGAPPE LIPIDS-7

CRP Ultra An Extremely ultra sensitive CRP which can detect any trace of Cardiac risk factors the others fails to find' C-reactive protein is an acute phase protein produced by liver. It measures low levels of C-reactive protein to identify low but persistent levels of inflammation. Several large scale prospective studies demonstrate that CRP Ultra is a strong independent predictor of future myocardial infarction and stroke among apparently healthy men and women. The American Heart Association (AHA) and Centre for Disease Control and Prevention (CDC) recommend the use of this high sensitive CRP...

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AGAPPE LIPIDS-8

Profile Packages Cholesterol End Point 5 x 25 mL / 5 x 100 mL / 4 x 250 mL Triglycerides End Point 4 x 50 mL / 5 x 25 mL / 5 x 100 mL AGHDL End Point 2 x 40 mL /2 x 60 mL AGLDL End Point 2 x 40 mL /2 x 60 mL Apo A1 End Point 1x30/1x5/1 mL Apo B End Point 1x30/1x5/1 mL CRP Ultra Fixed Time/End Point 1x18/1x9/1x2 mL Lipoprotein (a) Fixed Time 1x20/1x4/ 1 mL All kits are provided with Calibrator except Cholesterol & Triglycerides( Contains Standard). Lipid Profile SyRe packages are available for Fullyauto analyser like Biolis 24i. \/ AGAPPE DIAGNOSTICS SWITZERLAND GmbH Knonauerstrasse 54 - 6330...

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