DESIGNED FOR THE EVER-CHANGING COMBINATION THERAPY LANDSCAPE

PREDICTIVE SPATIAL SIGNATURES FOR THE NEXT GENERATION OF COMBINATION THERAPIES Get Higher Predictive Accuracy INTRODUCING PHENOCODE SIGNATURE Designed for the ever-changing combination therapy landscape The development of clinically useful biomarkers to select responders for combination therapies will be critical for the advancement of such treatments. A recent meta-analysis1 has shown that spatial phenotyping, enabled by multiplexed imaging, more accurately predicts patient response to antiPD-1/PD-L1 therapy than other biomarker modalities. Spatial signatures are a novel biomarker class developed...

IMMUNO-CONTEXTURE PANEL FLEXIBILITY TO ANSWER MORE QUESTIONS QUICKLY Decode the science of response to combination therapy PhenoCode Signature panels are designed to provide flexibility, allowing for the easy integration of one additional marker to a 5-plex panel. Analyze additional cell phenotypes or address your specific research question with your own marker of choice. IMMUNE PROFILE PANEL Where are the immune cells in the TME? ACTIVATED TIL STATUS PANEL Are the tumor cells proliferating or lymphocytes activated? PhenoCode™ Signature PhenoCode Signature 5-Plex Base Panels Where are the TAMs...

SPEED UP SPATIAL SIGNATURE DEVELOPMENT BY 3X THE PERFECT END-TO-END SOLUTION FOR SPATIAL SIGNATURE DEVELOPMENT PhenoCode Signature panels are optimized and validated to enable the rapid development of spatial signatures by shortening the assay development time by 3X. The development of spatial signatures requires a solution that easily integrates staining, imaging, and analysis using existing workflows while providing accuracy and reproducibility. ASSAY DEVELOPMENT AND OPTIMIZATION Custom-built 6-plex panel PhenoCode Signature 6-plex panel 3X REDUCTION CASE STUDY Spatial Signature Spotlight The...

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