AlbA HYPERTHERMIA SYSTEM 434MHz ■ Superficial 0/3cm ■ Semi-deep 4/6cm ■ Endocavitary

State of the Art Introduction Moderate heat is characterized by the property of being selectively toxic to cancerous cells. As a consequence, hyperthermia therapy has been developed based on the fact that tumour cells are more sensitive to temperature in the range of 40°C-45°C than normal tissue cells (Cavaliere et al., 1967). Several differences between normal and cancer cells are responsible for this selective sensitivity. Heat effectiveness on tumours, in fact, can be related to the peculiar combination of hypoxia, nutrient deficiency and acidosis characterizing tumour cells (Hildebrandt et...

State of the Art vectors and drug carriers. One of the most important limit to these attempts is that carriers cannot cross efficiently the vascular wall. Temperature sensitive liposomes (Kawai et al., 2005; Ahmed et al., 2004; Di Filippo et al., 2004; Kong et al., 2001), magneto liposomes (Lindner 2004; Matsuoka et al., 2004; Shinkai et al., 2001) could introduce interesting improvements as tumour blood flow and nanopartcles extravasion are selectively enhanced by mild hyperthermia (40-42°C) (Kong et al., 2001). Elastin-like polypeptides have been also investigated to provide a new way to thermally...

Water Bag RF Applicators & Tumours SAR data Technical data Size (x-y) Superficial recurrences ALFA emitting surface cm8,0 VOLUME (approx.) Breast carcinoma Technical data Recurrences breast carcinoma on thoracic wall Breast carcinoma BETA emitting surface cm15,0 Head & Neck Tumours VOLUME (approx.) Technical data Large recurrences breast carcinoma on thoracic wall Various origins adenopathy Superficial relapses of soft tissue sarcomas DELTA emitting surface cm20,0 VOLUME (approx.) Technical data Technical data

XZ Axis SAR Alignment XY Axis SAR Alignment probe The Alba Hyperthermia System represents a new generation of equipment designed to satisfy the clinical and the time/cost needs of today's oncological realities dedicated to adding loco regional hyperthermia treatments to standard Radiotherapy and Chemiothe-rapy procedures. ALBA is a compact integrated technology system characterized by a large choice of external and endocavitary effective applicators, all supplied with cooling water bags. Mini invasive temperature sensors and ultrasound black and white or colour doppler scanner units allow clinicians...

Real Time Temperature & Control Temperature Measurement The Alba Hyperthermia System has an integrated Multichannel Thermometer (from 4 to 16 channels) based on thermocouple Type T technology. A very quick sofisticated software measures the temperature of the sensors in real time. Sensors are completely free from electromagnetic artefacts or temperature drift due to the RF heating of the constantan/copper wires. The diameters (50µ) of the thermocouple wires together with measurement during a 1-second RF power suspension allows Alba to measure exactely the on site temperature data in respect to...

Real Time Blood Flow Multifrequency Convex Probe 6,0/7,5/9,0MHz Blood Flow Power Doppler Measurement OPTIONAL Blood Flow is a very important element that needs to be monitored before, during and after hyperthermia treatments. ALBA has, as an option, a special software that together with the display of the real time blood flow is able to detect, on demand, the rise or lowering of the local blood circulation. This special proprietary software measures the presence of blood, pixel by pixel, detecting the coloured spots in Power mode during the scanning time and assigning the percentage of variation...

Status & Patient Data Shows patient data and temperature in numeric order Real Time Emitted & Reflected Power Shows the transmitted and reflected power to help the operator to have a better RF coupling. Real Time Temperatures Temperature/time figure shows tissue and water temperature during treatment. Water Bag Thickness Increases and decreases water volume to optimize the RF coupling effect. Functions Sensor Temperature keys: F1 Pilot Sensor, F3 Duration, F4 Pilot Temperature, F5 Max Temperature To choose the pilot sensor, the pilot temperature and the max temperature allowed by other sensors....

Compact, Ergonomic & User Friendly Change applicators in less than 1 minute! The mechanical concept of the unit, its compact design and the double arms, one for the applicator and one for the touchscreen monitor, can be very useful and practical for any position needed in the treatment room. A special mechanical holder and a connector with a retention valve are very helpful to change the applicator in a very short time without water leakage and air bubbles. This is very useful when the applicator must be changed from one patient to another. Fingerprint module Power supply plug for monitor Movable...

Technical Assistance Internet/telephone connection and remote unit control: Alba allows operator to be connected via internet or direct telephone line to the technical assistance service. A web cam (optional) fixed on the unit monitor and Microsoft Messenger® real time chat communication are effective ways to connect the operator to the technician so as to solve any eventual needs very quickly. Thanks to a special software and the real time connection available on Alba a selfdiagnosis software helps to check and discover the broken module and organize the problem solution in very short time,...

Restek Diffusion Via di Vigna Stelluti, 14 - 00191 Roma Ph. +39 06 72672596 Fax +39 06 7235461 www.restekgroup.com [email protected] Restek Diffusion is the exclusive owner of the material held in the following brochure. Reproduction and diffusion, even partial, are strictly prohibited without specifically authorization of RD. All rights are reserved. In case of improper use, RD reserves the right to start legal proceedings.