ESR LINE
2Pages

20” Of gENIuS Results highly correlated to the Westergen reference method In accordance with CLSI requirements* 1.000 readings for each sample per test Use of the same EDTA tube coming from the CBC 175 μl of blood Self-cleaning without contamination Self-checking of reading sensors and physical obstacles Data transmission to LIS Efficiency and precision Standardization and reproducibility Certainty of results SCIENTIFIC PUBLICATIONS 1. CH Cha, CJ Park, YJ Cha, HK Kim, DH Kim, Honghoon, JH Bae, JS Jung, S Jang, HS Chi, DS Lee, HI Cho (Department of Laboratory Medicine, University of Ulsan College of Medicine and Gangneung Asan Hospital, Gangneung, Korea) “Erythrocyte Sedimentation Rate Measurements by TEST 1 Better Reflect Inflammation Than Do Those by the Westergren Method in Patients With Malignancy, Autoimmune Disease, or Infection” Am J Clin Pathol. 2009 Feb;131(2):189-94 2. B Frollano, G Cigliana, G Vitelli, R Fontinovo, S Giommi, I Cordone (Clinical Pathology, Regina Elena Cancer Institute, IFO, Rome – Italy) “Capillary Erythrocyte Sedimentation Rate (ESR) in oncological patients: low haematocrit pitfalls and sample collection optimization in a certified quality system laboratory” SIBioC National Congress 28-31 October 2008, Rimini, Italy. 3. R. Pajola, E. Piva, B. Robecchi, F. Tosato, M. Plebani. (Dep. of Laboratory Medicine, Padua University School of Medicine, Padua, Italy) “The Erythrocyte Sedimentation Rate (ESR): an old test with new contents” SIBioC National Congress 28-31 October 2008, Rimini, Italy. 4. J Reis, J Diamantino, N Cunha, F Valido (Clinical Pathology Department, IPO Coimbra; Francisco Gentil, EPE, Portugal),“Erythrocyte sedimentation rate in blood a comparison of theTest 1 ESR system with the ICSH reference method. Clinical Chemistry and Laboratory Medicine 2007 June; 45, Special Supplement, p.S118, MO77. 5. E Piva, R Pajola, V Temporin, M Plebani (Dept. of Laboratory Medicine, University-Hospital, Padova, Italy) “A new turbidimetric standard to improve the quality assurance of the erythrocyte sedimentation rate measurement” Clinical Biochemistry 2007 Apr; 40(7):491-5. Epub 2007 Jan 8. 6. Arikan S, Akalin N. (Biochemistry Department, Baskent University, Ankara, Turkey) “Comparison of the erythrocyte sedimentation rate measured by the Micro Test 1 sedimentation analyzer and the conventional Westergren method” Ann Saudi Med 2007; 27(5): 362-365. 7. LY Li, WB Chen, G Feng, SF Shen (Dep of Clinical Laboratory, Sixth People’s Hospital Affiliated to Shangai Jiaotong University, Shangai 200233, China) “Evaluation of the Microtest 1 ESR analyzer and investigation of the reference value” Chin J Lab Med, March 2007, Vol 30, N 3 (article in Chinese) EACH SAMPLE IS READ 1000 TIMES IN 20 SECONDS 8. S Ozdem, HS Akbas, L Donmez, M Gultekin (Clinical Biochemistry Unit, Medical Faculty, Central Laboratory, Akdeniz University, Antalya,Turkey) Comparison of TEST 1 with SRS 100 and ICSH reference method for the measurement of the length of sedimentation reaction in blood. Clin Chem Lab Med. 2006;44(4):407-12 TEST 1 is the only analyzer capable to give ESR results in 20 seconds by measuring the kinetic of red cells aggregation. 9. NE Ajubi, AJ Bakker, GA van den Berg (Stichting KCL, Dept. of Clinical Chemistry, Leeuwarden, The Netherlands), “Determination of the length of sedimentation reaction in blood using the Test 1 system: comparison with the Sedimatic 100 method, turbidimetric fibrinogen levels and the influence of M proteins” Clin Chem Lab Med 2006, 44 (7): 904-906 16. M Nicoli, E Lanzoni, A Massocco, (Laboratory of Clinical Chemistry and Haematological Analysis, Ospedale Civile Maggiore,Verona, Italy) “Integrated Haematology and Coagulation Laboratory”, Poster, Euromedlab Congress, 1-5 June 2003, Barcelona, Spain. 17. M Plebani (Dept. of Laboratory Medicine, University-Hospital, Padova, Italy), “Erythrocyte Sedimentation Rate: Innovative Techniques for an Obsolete Test?”, Clinical Chemistry and Laboratory Medicine, 2003, 41 (2): 115-116. 18. A Romero, M Muñoz, G Ramirez (Dept. of Haematology, H.C.U. “Virgen de la Victoria”, Málaga & *GIEMSA, School of Medicine, University of Málaga, Spain), “Determination of the Length of Sedimentation Reaction in Blood: a Comparison of the Test1 ESR System with the ICSH Reference Method and the Sedisystem”, Clinical Chemistry and Laboratory Medicine 2003, 41 (2). 19. D Giavarina, S Capuzzo, F Cauduro, M Carta, G Soffiati (Clin. Chem. & Hematol. Lab., San Bortolo Hospital, Vicenza, Italy), “Internal Quality Control for Erythrocyte Sedimentation Rate Measured Test 1 Analyzer” Clinical Laboratory 2002, 48:459-462. 20. E Heverin (Galway-Mayo Institute of Technology, Ireland), “Comparison of the Westergren method versus the TEST1 technique for determining the Erythrocyte Sedimentation Rate” May 2002, private communication. 21. BH Lee, J Choi, MS Gee, KK Lee, H Park (Dept. of Laboratory Medicine,Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea), “Basic Evaluation and Reference Range Assessment of TEST1 for the Automated Erythrocyte Sedimentatioon Rate” Journal of Clinical Pathology and Quality Control, Vol. 24, No. 1, 2002 (article in Korean). 22. E Piva, P Fassina, M Plebani (Dept. of Laboratory Medicine, University-Hospital, Padova, Italy), “Determination of the length of sedimentation reaction (erythrocyte sedimentation rate) in non-anticoagulated blood with the Microtest 1” Clin Chem Lab Med. 2002 Jul;40(7):713-7. 23. M Plebani, E Piva (Dept. of Laboratory Medicine, University-Hospital, Padova, Italy), “Erythrocyte Sedimentation Rate. Use of Fresh Blood for Quality Control”, American Journal of Clinical Pathology, 2002, 117:621-626. 24. D Smith D Spedding, (Dade Behring Diagnostics, New Zealand), “Evaluation of Agreement between the TEST1 and Starrsed Automated ESR Analysers”, November 2001, private communication. 25. D Giavarina, S Capuzzo, M Carta, F Cauduro, G Soffiati (Clin. Chem. & Hematol. Lab., San Bortolo Hospital, Vicenza, Italy), “Internal Quality Control for Erythrocyte Sedimentation Rate (ESR) measured by TEST-1 Analyzer”, Clinical Chemistry, June 2001, 47: 162. 10. Y Kagawa, N Ikeda, S Ito, S Makino, N Miyake (Clinical Test Section of Eiju Hospital, Finggal Link Co. and Dept. of Clinical Pathology of Juntendo University),“Evaluation for ESR automated measuring instrument with EDTA”, 36th Japan Society for Clinical Laboratory Automation, 30 September 2004, Japan. Aggregation Start 26. E Piva, MC Sanzari, G Servidio M Plebani (Dept. of Laboratory Medicine, University-Hospital, Padova, Italy), “Length of Sedimentation Reaction in Undiluted Blood (Erythrocyte Sedimentation Rate): Variations with Sex and Age and Reference Limits”, Clinical Chemistry and Laboratory Medicine, May 2001, 39: 451-454. 11. B Rosas, P Díaz, C Musa, J Aldunate (Servicio Laboratorio Clínico, Hospital Universidad de Chile),“Estudio Comparativo de 2 equipos que realizan VHS, Test1 y Vesmatic”, XII Congreso Chileno de Tecnologia Medica, 20–22 October 2004, Santiago, Chile (article in Spanish). TEST 1 CAPILLARY PHOTOMETRY TECHNOLOGY overcomes the variables and limitations of the sedimentation method also listed in the CLSI document*. 27. N de Jonge, I Sewkaransing, J Slinger, JJM Rijsdijk (Dept. Clinical Chemistry, Leyenburg Hospital, The Netherlands) Erythrocyte Sedimentation Rate by Test-1 Analyzer Clinical Chemistry, June 2000, 46: 881-882. 12. M Plebani, P D’Altoé, V Temporin, E Piva, M Buttarello, M Sanzari, (Dept. of Laboratory Medicine, UniversityHospital, Padova, Italy),“Variabilità Biologica Intra ed Interindividuale della Velocità di Eritrosedimentazione”, 36th SIBioC, 8-11 June 2004, Padova, Italy (article in Italian). Aggregation after 20 seconds 13. E Melkič, M Piskar, P Lenart (Klinični center Ljubljana, Klinični intitut za klinično kemijo in biokemijo) “Nov način merjenja hitrosti sedimentacije eritrocitov z analizatorjem Test1 Alifax”, 2 Kongres Hematologov in Transfuziologov Slovenije z Mednarodno UbeleÏbo, 23–24 April 2004, Portoroz, Slovenia (article in Slovenian). CAPILLARY PHOTOMETRY Temperature variability No dilution, use of EDTA tube Inadequate materials and pipettes variability Use of the same capillary for all samples Vibrations and pipettes verticality No influence of vibration or other external factors Not standardized sample mixing Automated mixing step Controls and Calibrators lack Latex Controls and Calibrators available Poor reproducibility 30. N Cirilli, Z Abu Asy, N Giacchè, F Bordicchia, S Paolucci, M Tocchini (Dept. of Laboratory Medicine, G. Salesi Hospital, Ancona, Italy), “TEST1: Un Nuovo Metodo per la Determinazione della VES”, Biochimica Clinica, Vol. 22, N. 5-6, 1998, p. 339. Independent from Hematocrit value Dilution problems using Sodium Citrate 29. G Soffiati (Clinical Chemistry and Hematology Laboratory, San Bortolo Hospital, Vicenza, Italy), “Nuovo Metodo per la Determinazione della Velocità di Eritrosedimentazione (VES)”, August 1998, private communication. Hematocrit influence 14. B Olivera Alonso, M Sirvent Monerris, MT Rotella Belda,V Ballenilla Antón, G Vidal (M Laboratorio Hospital San Vicente y Area Sanitaria 18.Alicante, Spain),“Cambio De Método Para La Determinación De V.S.G.: Repercusiones Sobre La Fase Preanalítica”, Generalitat Valenciana - Conselleria De Sanitat (for Valencia Government – MOH), Spain 2004 (poster in Spanish). 28. M Plebani, S De Toni, MC Sanzari, D Bernardi, E Stockreiter (Department of Laboratory Medicine, UniversityHospital of Padua, Italy) The TEST 1 automated system: a new method for measuring the erythrocyte sedimentation rate. Am J Clin Pathol. 1998 Sep;110(3):334-40. High reproducibility New ESR system generation * Clinical Laboratory and Standard Institute (formerly NCCLS) “Reference and Selected Procedure for ESR Test; Approved standard- 4th Edition” Vol.20 No.27; December 2000 15. P Galiano, “Quality and Automation in the Determination of the Erythrocyte Sedimentation Rate”, Symposium 046, 22nd World Congress of Pathology & Laboratory Medicine, 30 August- September 2003, Busan, Korea. ALIFAX S.p.A. Via F. Petrarca, 2/1 35020 Polverara - Padova, ITALY Tel. +39 049 0992000 Fax +39 049 5855434 info@alifax.com www.alifax.com Entered in Padova companies register at the n. 04337640280. Company stock € 6.000.000 entirely deposited Company with single partner