POLYPURE® S+ High Flux Series STEA M POLYPURE® S+ Allmed’s high flux dialyser, superbly balancing middle molecule removal, optimal albumin retention, whilst offering excellent levels of endotoxin protection consistent with POLYPURE® membranes. All feature the additional advantages of autoclaved steam sterilisation. Steam sterilisation in autoclave: best for patients & the environment • No potentially dangerous substances are generated during autoclaved steam sterilisation 
 • Lower priming volume requirements compared to other sterilisation methods for the same product (see DFU) 
 • Optimised rheology during clinical use 
 • Autoclave steam sterilisation is the only steam sterilisation recognised by The International Pharmacopeia (Methods of Sterilisation–VI Edition) • Less impact on the environment compared with irradiation and ethylene oxide Excellent balance between middle molecule removal and albumin retention: safeguarding the patient nutritional status The membrane structure perfects the delicate balance between substantial middle molecule removal whilst preserving levels of albumin. POLYPURE® S+ removes 85% of ß2 microglobulin with only 0.6g of albumin loss, during a session of post dilution HDF. PROTECTION FROM PYROGENS Adsorption into the wall Sieving/ size exclusion REDUCED INFLAMMATION BEST IN DIALYSIS THERAPY Albumin ALBUMIN RETENTION Allmed | POLYPURE® S+ High Flux Series | allmedgroup.com

Allmed | POLYPURE® S+ High Flux Series | allmedgroup.com Clearance in vitro (ml/min) QD = 500 ml/min
 QF = 0 ml/min
 T = 37oC Max TMP = 500mmHg Blood priming Volume (ml) Sieving coefficient • Performance data was measured in vitro according to standard ISO 8637 • UF measurement: using bovine/human blood (Hct 32%;protein 60g/l) • Typical values obtained with an individual batch of fibres, clinical use may illustrate a difference in results in relation to different Ultrafiltration/measuring techniques and possible variation between batches of fibres Membrane material Micro-undulated polysulfone...