POLYPURE® S Mid Flux Series STEA M POLYPURE® S–Allmed’s middle flux dialyser with optimal clearances. Offering excellent endotoxin protection consistent with Allmed membranes with the additional advantage of autoclaved steam sterilisation. Micro-undulated technology: highest efficacy Micro-undulation technology ensures the highest efficiency and clearances thanks to “bundles” and “dead-zones” prevention, together with the optimally increased surface exchange of blood-membrane-dialysate. Autoclaved steam sterilisation:
the best for patients & the environment • No potentially dangerous substances are generated during autoclaved steam sterilisation 
 • Lower priming volume requirements compared to other sterilisation methods for the same product (see DFU) 
 • Optimised rheology during clinical use 
 • Autoclave steam sterilisation is the only steam sterilisation recognised by The International Pharmacopeia (Methods of Sterilisation–VI Edition) • Less impact on the environment compared with irradiation and ethylene oxide Protection from endotoxins: reduced inflammation POLYPURE® asymmetrical membrane with an optimised micro-undulated fibre structure and 40μm thickness, enhances the membrane’s ability to prevent endotoxin transfer due to its geometrical and adsorptive capacity capability. Systemic inflammation is well recognised to be associated with an increased cardiovascular disease risk in patients with chronic renal disease. Exposure to endotoxins results in a release of a wide variety of pro-inflammatory cytokines, with subsequent chronic systemic inflammation and a broad range of negative cardiovascular effects. Chronic inflammation can also modify the process of erythropoiesis and probably induces resistance to erythropoietin. Allmed | POLYPURE® S Mid Flux Series | allmedgroup.com Adsorption into the wall Sieving/ size exclusion Safe dialysis bacteria free apyrogenic 40 µm prot

Allmed | POLYPURE® S Mid Flux Series | allmedgroup.com Clearance in vitro (ml/min) QD = 500 ml/min
 QF = 0 ml/min
 T = 37oC Max TMP = 500mmHg Blood priming Volume (ml) • Performance data was measured in vitro according to standard ISO 8637 • UF measurement: using bovine/human blood (Hct 32%;protein 60g/l) • Typical values obtained with an individual batch of fibres, clinical use may illustrate a difference in results in relation to different Ultrafiltration/measuring techniques and possible variation between batches of fibres Membrane material Micro-undulated polysulfone Housing material Polycarbonate...