NEUROSCIENCE PRODUCTS Simplifying neuroscience research with ALZET Osmotic Pumps ALZET® Osmotic Pumps and Brain Infusion Kits have been used in cutting edge neuroscience research for nearly 4 decades. Their ability to circumvent the bloodbrain barrier (BBB) and administer agents directly to the central nervous system (CNS) has enabled new and exciting discoveries in the study of neuropathic pain, cerebral ischemia, neurodegenerative diseases, and more. BENEFITS OF ALZET PUMPS IN NEUROSCIENCE RESEARCH • Small size for use in mice and young rats • Direct delivery across the blood-brain barrier • Continuous and controlled delivery of neuroactive compounds • Ideal for behavioral studies — no animal handling required during infusion • Easy attachment to a catheter for delivery to the brain, spinal cord, or peripheral nerves • Well-established neuroscience method with over 15,000 publications Subcutaneous placement of an ALZET pump and brain cannula enables automatic and continuous delivery of agents to the CNS of unrestrained lab animals. Neuroscientists have also capitalized on the ALZET pump’s ability to deliver a precise and continuous dose, without researcher intervention or animal disturbance, for using them in behavioral studies. Gathered here is a selection of CNS infusion tools to help you achieve reliable and reproducible results. • Improved bioavailability of short halflife peptides and proteins • Convenient & cost-effective for chronic dosing of lab animals • Automatic nighttim

ALZET pumps and brain infusion kits are a reliable and convenient tool to deliver agents across the BBB, and directly to their site of action in the brain. They enable continuous delivery of a precise drug dose, and ensure that sufficient levels are maintained at the target location to elicit their effects. ALZET brain infusion kits can be used in two ways: • Infusion into the cerebral ventricles, exposing a wide variety of brain regions to the infusate via the cerebrospinal fluid. • Direct microinfusion of discrete brain structures, resulting in localized distribution of infusate in the target...

Medical grade polyethylene and vinyl catheters are available for multiple targeted delivery applications. Specifically designed for use with ALZET pumps, these catheters are constructed with high quality materials for increased patency and reduced tissue trauma. They incorporate useful features, such as flexible and secure catheter junctions to minimize kinking and leaking, and a teflon-coated, stainless steel wire to facilitate placement. They are available sterile and individually packaged. Additional catheters are available for other targeted delivery applications. Visit our website at www.alzet.com,...

The AutoClip & Reflex wound closure systems provide a fast and effective alternative to sutures for closing incisions made for ALZET pump implantations. The components are available separate, or as a kit containing the Applier, Remover, and stainless steel wound clips (7 mm or 9 mm). The 9 mm AutoClips are ideal for use in rats, while the 7 mm Reflex clips are optimum for use in mice and young rats. Visit www.alzet.com, or contact us for a complete list of wound closure products available. CYANOACRYLATE ADHESIVE (LOCTITE 454) Loctite 454 is an instant adhesive gel for use with ALZET Brain Infusion...