Hyaluronic Acid Single Injection Product Brochure Long-lasting pain relief for shoulder, hip, knee & ankle The market-leading single injection viscosupplement utilised to treat joint pain caused by osteoarthritis.

Hyaluronic Acid Single Injection Monovisc is now indicated for the treatment of the symptoms of mild to moderate osteoarthritis of the shoulder, hip, knee, and ankle joints. Extended residence time Patented cross-linking process slows down degradation to stay in the joint longer so its actions last longer, leading to longer pain relief.5 Responder rate at 6 months Extended pain relief Up to 39 weeks of clinically proven efficacy with a single injection in the knee6 92.4% of patients whose knee joints ^ were treated with Monovisc responded positively in the areas of pain, stiffness, and physical...

Monovisc is formulated to mimic the properties of endogenous HA7,8 In human joints, endogenous HA is present in the cartilage extracellular matrix and synovial fluid and has several functions, including: Mechanical effect Anti-inflammatory effect HA binds well to water, producing a viscous, jelly-like consistency that provides lubrication and acts as a shock absorber within the joint. HA plays an important role in reducing joint inflammation and pain caused by injury or tissue degeneration.8,9 Analgesic effect Chondroprotective effect HA diminishes nerve impulses and the sensitivity of nociceptive...

Monovisc™ High Concentration of HA (22 mg/ml)10 Creates a high viscosity environment to replicate healthy joint function12 Leads to longer residence time in joint and better viscoelasticty of synovial fluid5 Optimal High Molecular Weight HA Ultra Pure Non-Avian HMW HA Results in greater pain reduction and longer duration of effect than low molecular weight HA12,15 Produced by bacterial fermentation with complaint data under Post Market Surveillance over 14 years demonstrating an excellent safety profile in all joints with a very low patient reaction complaint rate of 0.01%10,16,17 Monovisc is...