AB-306-AA042
AB-306-AA042
The document describes a monoclonal antibody (mAb) specific to Inhibin B/Activin B (BetaB subunit) with species reactivity in humans. It is sourced from murine and purified using Protein G from hybridoma culture supernatant. The product is a clear, colorless solution with a concentration that is batch-specific, as detailed in the Certificate of Analysis. The isotype is IgG1, and its activity is determined by direct ELISA. The package size is 100 µg, and it is composed of Phosphate Buffered Saline, 10mM, pH 7.4, without preservatives.
The antibody is provided in a liquid format, so reconstitution is not applicable. It is shipped on dry ice and should be stored at -20°C to -80°C to avoid repeated freeze-thaw cycles.
The product is recommended for use in Western Blotting and as a Neutralizing Antibody, with suggested concentrations of 10-30 ng for Western Blotting and 1-5 µg/mL for neutralizing applications. Optimal dilutions should be determined by each laboratory.
The document cites several studies and publications that have utilized this antibody in various research contexts, including studies on human epicardial adipose tissue, colon cancer cell migration, ovarian tumors, pulmonary fibrosis, pancreatic cancer, and acute pancreatitis.
Catalog excerpts
Activin B mAb AB-306-AA042 description Pricing: $1400 - 100 gg Inquire about other package sizes and bulk pricing. specifications Specificity Inhibin B/Activin B (BetaB subunit) Source Murine Product Form / Appearance Clear, Colorless solution Species Reactivity Human Product Type Monoclonal Antibody Purification Purified from hybridoma culture supernatant using Protein G. Concentration Batch Specific - refer to Certificate of Analysis Isotype IgGI report Activity Determined by direct ELISA Composition Phosphate Buffered Saline, 10mM, pH 7.4 (no preparation and storage Reconstitution Not Applicable. Provided in liquid format. Shipping Conditions This product is shipped on dry ice. Upon receipt, store it immediately at the temperature recommended below. Storage Store at -20°C to -80°C as supplied. Avoid repeated freeze-thaw cycles. applications This product has been reported to work in the following applications. This information is derived from testing within our laboratory, peer-reviewed publications or personal communications from the originators. Optimal dilutions should be determined by each laboratory for each application. Status Recommended Concentration Western Blotting Recommended 1-5 pg/mL application images 445 Medical Center Blvd. • Webster, TX • Tel: (281) 404-0260 www.AnshLabs.com • [email protected]
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REFERENCES OR CITATIONS Conover CA, Bale LK, Frye RL, Schaff HV. Cellular characterization of human epicardial adipose tissue:highly expressed PAPP-A regulates insulin-like growth factor I signaling in human cardiomyocytes. Physiol Rep. 2019;7(4):e14006. doi:10.14814/phy2.14006 Jana A, Das A, Krett NL, Guzman G, Thomas A, Mancinelli G, Bauer J, Ushio-Fukai M, Fukai T, Jung B. Nuclear translocation of Atox1 potentiates activin A-induced cell migration and colony formation in colon cancer. PLoS One. 2020 Jan 21;15(1):e0227916. doi: 10.1371/journal.pone.0227916. Lambert-Messerlian G, Steinhoff M,...
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