Apex Medical Corp. PVA Pressure Variation Algorithm The PVA Pressure Variation Algorithm is a technology designed to provide relief to patients who experience CPAP pressure discomfort by reducing pressure at the start of exhalation and return to the prescribed pressure at the commencement of inhalation. Pressure can be reduced by three different level settings, allowing the delivery of prescribed pressure at a time when the patient needs it most without compromising comfort and compliance. The PVA technology is available on CPAP and APAP modes. [1 Reduce pressure during the transition from Inspiration to Expiration. 3 Maintain lower pressure level (depending on the PVA setting) during Expiration phase. S Return to therapeutic pressure in the end of Expiration phase. Or PVA and apnea detection In order to ensure the effectiveness of CPAP therapy, PVA will be automatically suspended if apneas are detected. After apneas disappear, PVA will re-start. Effective Auto Algorithm: Reduce AHI & Improve SpO2 via strict clinical proof * Koji Narui, et al., ASRS. 2012. Sleep Center, Toranomon Hospital, Tokyo, Japan USA Apex Medica1 USA Corp. 615 N. Berry St. Suite D, Brea, CA 92821, USA T +1 714 671 3818 F +1 714 671 9040 [email protected] MinSpO2 was significantly improved from 80.7 ± 4.9 % to 92.3 ± 3.7 % Easy assembly and disassembly of the water chamber with a simple hook and lock design Clear backlit LCD display and Small footprint to be easily intuitive user interface for easy packed into carry-on luggage iCH seriesContinuous Positive Airway Pressure Distributed by Print-2017/03-1000 A11 rights reserved Specifications may change without notice. www.apexmedica1corp.com Providing comfortable and flexible therapy modes, the iCH series CPAP system with it's stylish and attractive design is the perfect partner to support you and your prescribed treatment goals. The i n teg rate d he a ted humi d i fi er provid e s com for table, qui e t and reliable therapy and for people on the move, this CPAP therapy system is lightweight, compact and very sleek. The iCH is a CPAP that doesn't look like a CPAP; its elegant design allows you to place it anywhere in your home. Care for a Healthy Life

Apex Medical Corp. iCH series Apex Medical Corp. iCH series Holistic Healthcare Formula [Compliance]3+[Elegance]=Lifestyle The launch of the iCH series CPAP by Apex introduces a modern and exciting concept: The Holistic Healthcare Formula [Compliance]3+[Elegance] = Lifestyle [Compliance]3 An alternative definition to enhance the improvement of CPAP therapy and improve the patient's well-being is no longer a myth. Upholding the advancement of patient's lifestyles and improving clinical conditions, iCH compliance technology has: 1. Stable and precise pressure output 2. PVA pressure relief technology...