Ophthalmic Squeeze Dispenser
Ophthalmic Squeeze Dispenser
The Ophthalmic Squeeze Dispenser Technology Platform offers a versatile solution for preservative-free ophthalmic formulations. It supports a wide range of customized configurations and applications, making preservatives like Benzalkonium Chloride obsolete.
- Utilizes purely mechanical Tip-Seal technology, eliminating the need for preservatives and additives.
- Ensures a metal-free fluid pathway and no filtering of formulations.
The dispenser operates by increasing pressure inside the system when the bottle is squeezed, causing the Tip-Seal to open and release a drop. Key components include an air filter, applicator, spring, centerpiece, spray pin, and Tip-Seal.
- TSIT 2.0: Ensures integrity against Pseudomonas aeruginosa, Staphylococcus Aureus, and Candida Albicans.
- CVIT: Tests closure and filter integrity with Bacillus atrophaeus spores.
- First FDA-reviewed technology for multidose preservative-free systems.
- Complies with FDA and BfArM regulations.
- Cap Options: Standard, Liner, Pure, available in various colors.
- Flow Control: Wide range of settings for different formulations.
- Container Options: Standard, Soft, Pure bottles, available in various sizes and sterilization methods.
Aptar Pharma offers comprehensive service packages, including regulatory affairs support, analytical lab services, and a global CMO/CDMO network.
Catalog excerpts
Ophthalmic Squeeze Dispenser Technology Platform Delivering solutions, shaping the future.
Open the catalog to page 1
Ophthalmic Squeeze Dispenser The versatile multidose technology platform for preservative-free ophthalmic formulations Multidose Preservative-Free System Makes Preservatives Obsolete Preservatives in Eye Care formulations, such as Benzalkonium Chloride (BAC), can lead to side effects with chronic use. The Ophthalmic Squeeze Dispenser represents a worldwide-accepted solution to address this challenge. Key Benefits • urely mechanical Tip-Seal technology eliminates the need for preservatives and additives, P such as silver ions or surface coating • No filtering of formulation • etal-free fluid pathway...
Open the catalog to page 2
• ptar Pharma’s Tip-Seal technology has been qualified by the industry’s most A challenging tests and has passed worst-case scenario simulations Proven Unrivalled Microbiological Safety Helps Ensure Patient Safety • omprehensive data package C (Tip-Seal Integrity Test) (Closure Ventilation Integrity Test) Submersed actuation in challenge suspension containing Pseudomonas aeruginosa, Staphylococcus Aureus and Candida Albicans. Reflects most recently updated guidelines in highly regulated markets. Closure and filter challenge with Bacillus atrophaeus spores in aerosol chamber. FDA-Reviewed Technology...
Open the catalog to page 3
Versatile Technology Platform Offers Easy Customization Solutions for the Ophthalmic Squeeze Dispenser The technology platform allows for a wide range of customized configurations and applications for specific ophthalmic formulations. Cap Options • Standard Cap / Liner Cap/ Pure Cap • Caps available in various colors Liner Cap Functional Options Pure Pin Ultra-clean COC material for sensitive formulations Flow Control W ide range of flow control settings for various formulation properties * llustrated in blue for I visualization purposes only. Filter Protection Valve TPE one-way duckbill valve...
Open the catalog to page 4All Aptar catalogs and technical brochures
VP3 Technology Platform2 Pages
Airless+4 Pages
Bag-on-Valve4 Pages
