Not hazardous Not hazardous Not hazardous Not hazardous MITI Amount Yttrium Oxide Hafnium Oxide (as Hafnium) Exposure Limit Aluminum Oxide 5 mg/m3 TWA (respirable), 10 mg/m3 TWA (total dust) SECTION 9: Physical and Chemical Properties 9.1. Information on basic Physical and Chemical Properties: White solid block or slab Not applicable Not determined Not applicable Not flammable None None known. Avoid dusty conditions. None known. None known. Potential Health Effects: Inhalation: Dust may cause irritation of the upper respiratory tract with coughing and difficulty in breathing. Skin Contact: Prolonged skin contact may cause mechanical irritation. Eye Contact: Dust may cause mechanical irritation with redness and tearing. Ingestion: Swallowing large amounts may cause gastrointestinal irritation and nausea. Acute Toxicity: Zirconium Oxide: Yttrium Oxide: Hafnium Oxide: Aluminum Oxide: Skin corrosion/irritation: Eye damage/ irritation: Skin Sensitization: Respiratory Sensitization: Germ Cell Mutagenicity: Carcinogenicity: SECTION 12: Ecological Information Zirconium Oxide: Yttrium Oxide: Hafnium Oxide: Aluminum oxide: NOEC 48 hr daphnia magna >100 mg/L, 12.5 Results of PVT and vPvB assessment: 12.6 Other Adverse Effects: ArgenZ HT+ArgenZ HT+ Multilayer SAFETY DATA SHEET This SDS conforms to Regulation (EU) No 1907/2006 and 20516/830, US Hazcom 2012 (29 CFR 1910.1200) and Canadian WHMIS 2015 Product Name: ArgenZ HT+, ArgenZ HT+ Multilayer Product Use: Ceramic Blocks for Crowns and Bridges Manufacturer: The Argen Corporation J 5855 Oberlin Drive San Diego, CA 92121 U.SA CHEMTREC: 1-703-741-6090 (Collect calls accepted) For information contact Regulatory Affairs; [email protected] SDS Date of Preparation/Revision: May 2017/ Rev. A OSHA Hazcom 2012 /WHMIS 2015 Classification: : Not Hazardous CLP/GHS Classification (1272/2008) Not Hazardous 2.2. Label elements None Required 2.3. Other hazards None Identified Zirconia (Zirconium Oxide) Yttria (Yttrium Oxide) Hafnium Oxide Aluminum Oxide INHALATION: Remove to fresh air. If irritation or difficulty in breathing occurs, get medical attention. SKIN CONTACT: No first aid is required. Wash skin with soap and water. If irritation develops, get medical EYE CONTACT: Flush eyes with large quantities of water, holding the eyelids apart.If irritation persists consult INGESTION: No adverse effects expected. If large amounts are swallowed or if irritation or discomfort occurs, get medical attention. 4.2. Most Important symptoms and effects, both acute and delayed: May cause mechanical eye irritation. Prolonged skin contact may cause mechanical irritation. Inhalation of dust may cause upper respiratory tract irritation. 4.3. Indication of any immediate medical attention and special treatment needed: Immediate medical attention is not required. 5.1 Extinguishing Media: Use media appropriate for the surrounding fire. 5.3 Advice for Firefighters: Firefighters should wear positive pressure self-contained breathing apparatus and full protective clothing for fires in areas where chemicals are used or stored. Cool fire exposed containers with water. 6.1 Personal Precautions, Protective Equipment and Emergency Procedures: Wear appropriate protective clothing and equipment. Avoid contact with eyes. Avoid breathing dust. 6.2 Environmental Precautions: Report releases as required by local and national authorities. 6.3 Methods and Material for Containment and Cleaning Up: Sweep up avoiding creating airborne dust and place into an appropriate container for disposal. Wash spill area with a damp cloth to remove residue. 6.4 Reference to Other Sections: Refer to Section 8 for personal protective equipment and Section 13 for disposal information. 7.1 Precautions for Safe Handling: Avoid contact with eyes. Wash thoroughly after handling. Keep containers closed when not in use. Do not reuse containers. 7.2 Conditions for Safe Storage, Including any Incompatibilities: Store as directed on package insert. Industrial uses: None identified Professional uses: Ceramic Material for Dental Prosthetics Recommended Monitoring Procedures: None. Appropriate Engineering Controls: Use adequate general or local exhaust ventilation to minimize exposures levels. Personal Protective Measurers Respiratory Protection: None normally required. If the exposures are excessive and irritation is experienced an approved dust/mist respirator appropriate for the form and concentration of the contaminants should be used. Selection and use of respiratory equipment must be in accordance with applicable regulations and good industrial hygiene practice. Eye Protection: Wear safety glasses if contact is possible. Skin Protection: None required. Wash hands thoroughly after handling. Other protection: Protective clothing as required to avoid prolonged skin contact. Melting/Freezing Point: Initial Boiling Point/Range: Flash Point: Evaporation Rate: Flammability: (solid/gas) Flammable/ Explosive Limits: Vapor Pressure: Vapor Density: Relative Density /Specific Gravity: Solubility in Water: Partition Coefficient: (n-octanol/water) Auto-ignition Temperature: Decomposition Temperature: Viscosity: Explosive Properties: Oxidizing Properties: 10.6 Hazardous Decomposition Products: SECTION 11: Toxicological Information 11.1 Information on Toxicological Effects: Oral rat LD50 >5000 mg/kg, Inhalation rat LC50 >4.3 mg/L/4 hr (no mortalities, maximum attainable concentration) Oral rat LD50 >5000 mg/kg, Inhalation rat LC50 >5.09 mg/L Oral rat LD50 >5000 mg/kg, Inhalation rat LC50 >4.3 mg/L/4 hr (no mortalities, maximum attainable concentration) Oral rat LD50 >10000 mg/kg; LC50 Inhalation rat >2.3 mg/L/4 hr None of the components cause skin irritation or corrosion. None of the components cause eye irritation or corrosion. Expected to cause mechanical eye irritation. None of the components are skin sensitizers. No data available. Not expected to cause respiratory sensitization. None of the components cause germ cell mutagenicity. None of the components are listed as a carcinogen or potential carcinogen by IARC, NTP, ACGIH, OSHA or the CLP. Developmental / Reproductive Toxicity: None of the components have been shown to cause reproductive or developmental toxicity. Specific Target Organ Toxicity (Single Exposure): No data available. Specific Target Organ Toxicity (Repeated Exposure): No data available 72 hr EC50 Desmodesmus subspicatus >100 mg/L 96 hr LL50 Danio rerio >100 mg/L, 72 hr EL50 Desmodesmus subspicatus >100 mg/L 96 hr LC50 Danio rerio >100 mg/L, 72 hr EC50 Pseudokirchnerella subcapitata >100 mg/L NOEC 96 hr Salmo trutta >100 mg/L, NOEC 72 hr Selenastrum capricornutum >100 mg/L Biodegradation is not applicable to inorganic substances. No data available No data available None required. None known. 13.1. Waste Treatment Methods: Dispose in accordance with all national and local regulations. 14.6 Special Precautions for User: None identified 14.7 Transport in Bulk According to Annex III MARPOL 73/78 and the IBC Code: Not applicable - product is transorted only in packaged form. SARA Section 313 (40 CFR 372): This product contains the following toxic chemical(s) subject to reporting requirments of SARA 313: None SARA Section 311/312 (40 CFR 370) Hazard Categories: Not hazardous Comprehensive Environmental Response and Liability Act of 1980 (CERCLA): This product is not subject to CERCLA reporting requirements. Many states have more stringent release reporting requirements. Report spills required under federal, state and local regulation CERCLA SECTION 103: This product is not subject to CERCLA reporting requirements; however, many states have more stringent release reporting requirements. Report spills required under federal, state and local regulations. European Regulations: Other EU Regulations: This product is classified and labeled in accordance with EC Directives. This Safety Data Sheet complies with the requirements of Regulation (EC) No 1907/2006 (REACH) Japanese Regulations: Manufacture Prohibited: Not applicable Manufacture Allowed: Not applicable Notification Obligation: Not applicable Labeling Obligation: Yttrium Comp >1% - Hafnium Comp >1% - Aluminum Oxide >1% SDS Obligation: Yttrium Comp >1% - Hafnium Comp >1% - Aluminum Oxide >1% Poisonous and Deleterious Substances Control Law (PDSCL): None of the chemicals are listed. Pollutant Release and Transfer Register (PRTP): None of the chemicals are listed. Law Concerning the Protection of the Ozone Layer: None of the chemicals are listed. Fire Service Law: None of the chemicals are listed. Ship Safety Act: None of the chemicals are listed. Aviation Law: None of the chemicals are listed. Air Pollution Control Law: None of the chemicals are listed. Water Pollution Control Act: None of the chemicals are listed. Soil Contamination Countermeasures Law: None of the chemicals are listed. Offensive Odor Control Law: None of the chemicals are listed. Act on Prevention of Marine Pollution and Maritime Disaster: None of the chemicals are listed. International Inventories US EPA TSCA Inventory: All of the components of this product are listed on the Toxic Substances Control Act (TSCA) Chemical Substances Inventory or exempt. Canadian Environmental Protection Act: All of the components in this product are listed on the Domestic Substances List (DSL) or exempt. European Union: All the components in this product are listed on the EINECS inventory or exempt. China: All of the components in this product are listed on the Inventory of Existing Chemical Substances in China (IECSC) or exempt. Japan: All of the components in this product are listed on the Japanese Existing and New Chemical Substances (ENCS) inventory or exempt. Korea: All of the components in this product are listed on the Korean Existing Chemicals List (KECL) or exempt. New Zealand: All of the components in this product are listed on the New Zealand Inventory of Chemicals (NZIoC) or exempt. Taiwan: All of the components of this product are listed on the National Existing Chemical Inventory (NECI) in Taiwan or exempt. 15.2 Chemical Safety Assessment: None required NFPA Rating: Fire: 1 Health: 2 Instability: 0 GHS Classification for Reference (See Sections 2 and 3): None Revision Summary: Converted to GHS -0 All Sections Revised. The information and recommendations set forth herein (hereinafter "information") are presented in good faith and believed to be correct as of the date hereof. However, The Argen Corporation makes no representations as to the completeness of accuracy thereof and information is supplied upon the condition that the persons receiving the above material will make their own determination as to its suitability for their purposes prior to use. In no event will "The Argen Corporation" be responsible for damages of any nature whatsoever resulting from the use of or reliance upon information. No representations or warranties, either expressed or implied, or merchantability, fitness for a particular purpose or of any other nature are made hereunder with respect to information or the product to which information refers.