High-speed piezo solution switcher.


Catalog excerpts

High-speed piezo solution switcher. - 1

Piezo Switcher Low-profile variation High-speed piezo solution switcher. Performance Specifications PZT head • Travel 300 μm • Minimum controllable motion 0.3 nm • Command input –10 V to +10 V MX1640 manual manipulator • Maximum load 2 lbs • Travel / axis 0.80 inch [20 mm] • Minimum controllable motion 5 μm Fast piezo solution switcher The piezo solution switcher uses a high-speed piezo flexure guided nanopositioner to move pipette tips in solution switching applications. It can move an electrode tip across a 5 μm thick theta glass septum. This system is ideal for measuring cellular response to drugs or other elements in solution. Piezo movement can be triggered by either input from common recording amplifier equipment or by Siskiyou software via a LabVIEW™ interface that can control distance, frequency and dwell time. The piezo also includes the piezo amplifier box and the Input-Shaping® board, which significantly reduces pipette tip vibration and can be programmed to virtually eliminate resonances from your specific system. The piezo flexure guided nanopositioner is mounted to our ultra-stable MX1640 crossed roller micromanipulator. The MX1640 has 20mm of travel in all four axes. The fourth axis can be set at any angle to select the desired approach angle. This adjustable fourth axis incorporates our MXC-45 to allow rotation of the piezo/pipette assembly up and out of the experiment for easy glass replacement. The base of the MX1640 also has a built-in coarse adjustment for rotation of the entire manipulator, or can also be used with our MX-RS rotation stage for mor

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High-speed piezo solution switcher. - 2

Rapid Pipette Sweeping: Eliminating Unwanted Switching Rapid theta-glass transitions cause ringing of the mechanical structure. Zoomed-in view at target position. White: vibrometer real-time position output. Red: HEKA amp current. Correlation between physical position and HEKA amp output is evident. The vibration of the theta-glass pipette assembly causes repetitive switching of the patch-clamp signal. Same as graph above, using patented vibration-cancellation technology. The undesirable rapid switching of the HEKA amp output (red) due to rapid recoil-driven structural oscillations of the...

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