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InFocus™

InFocus™

InFocus™

Product catalog summary
Overview
The document introduces the Axcend Focus LC® and InFocus™ as advanced tools for real-time reaction monitoring, crucial for scientific breakthroughs and process optimizations. These tools provide fast, accurate, and reliable data, enabling real-time, in-line, on-line, and at-line analysis to detect inefficiencies, optimize reactions, and improve product quality.

In-Line Monitoring
The Axcend InFocus continuously samples directly from the reaction stream, providing real-time HPLC data without disrupting the process. This allows for immediate detection of impurities, tracking of reaction progress, and on-the-fly adjustments to optimize yield and reduce waste.

At-Line Monitoring
For workflows requiring frequent but controlled sampling, the InFocus enables on-demand HPLC analysis right next to the reactor. This allows operators to pull samples as needed, analyze them quickly, and make data-driven decisions without waiting for lab results.

On-Line Monitoring
With automated sampling and analysis at set intervals, the InFocus helps maintain process stability, prevent deviations, and optimize batch-to-batch consistency, ensuring product quality while minimizing manual intervention.

Key Features
  • Compact Design: Fits in lab hoods or next to reaction vessels.
  • Automated Workflow: Reduces manual effort with unattended sampling and analysis.
  • Versatile Reaction Monitoring: Tracks batch or continuous processes, even with limited sample availability.
  • Accurate Results: Optimized preparation minimizes false positives and background noise.
  • Flexible Configuration: Customizable valves support diverse workflows.

Technical Specifications
  • Dimensions: 22.8 x 24.2 x 23.3 cm
  • Weight: 5.4 kg
  • Pump System: Bi-directional, 1500psi, 5.0 nL/min - 5.0 mL/min programmable
  • Valves: Multiple 5000psi multiposition and switching valves
  • Injection Volume: 0.1 - 50.0 µL
  • Operating Conditions: 4 - 45 °C, max 80% relative humidity
  • Solvent Compatibility: Typical RP/NP mobile phases, pH range 2.0-10.0
  • Electrical Power: 100-240 VAC, 50/60 Hz
  • Communication: USB
  • Software Control: InFocus Routine Designer

Conclusion
The Axcend Focus LC® and InFocus™ provide a compact, automated solution for real-time reaction monitoring, offering unparalleled sample preparation and analysis capabilities. Their integration into scientific workflows enhances decision-making and process optimization, leading to better outcomes.
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Catalog excerpts

InFocus™-1

Axcend InFocus™ Faster Insights. Smarter Decisions. Better Outcomes. Real-time reaction monitoring with the Axcend Focus LC & InFocus™ ® Scientific breakthroughs and process optimizations require fast, accurate, and reliable data. As a Process Analytical Technology (PAT) tool, the InFocus enables real-time, in-line, on-line, and at-line analysis, allowing scientists and engineers to detect inefficiencies, optimize reactions, and improve product quality without delays. Seamlessly integrating with the Axcend Focus LC, this compact, automated system provides unparalleled sample preparation and analysis, delivering immediate, actionable insights right at the reaction site—whether in a fume hood or directly next to the vessel. In-Line Monitoring The Axcend InFocus continuously samples directly from the reaction stream, providing real-time HPLC data without disrupting the process. This ensures immediate detection of impurities, reaction progress tracking, and on-the-fly adjustments, optimizing yield and reducing waste. At-Line Monitoring For workflows requiring frequent but controlled sampling, the InFocus enables on-demand HPLC analysis right next to your reactor. Operators can pull samples as needed, analyze them within seconds, and make data-driven decisions—without waiting for lab results. On-Line Monitoring With automated sampling and analysis at set intervals, the InFocus helps teams maintain process stability, prevent deviations, and optimize batch-to-batch consistency. This approach is ideal for ensuring product quality while minimizing manual interve

 Open the catalog to page 1
InFocus™-2

Technical Specifications Dimensions (WxDxH) Compact Design Fits in lab hoods or next to reaction vessels. Pump System Bi-directional, 1500psi, 5.0 nL/min - 5.0 mL/ min programmable 2 x 5000psi multiposition, 2 x 5000psi 2-position; 3x 5000 psi LDV switching valves (standard configuration: 2x 3-port 2-position, 1x 6-port 2-position for automated online sampling/filtering with automated filter backflush) Injection Volume 0.1 - 50.0 µL (> with multiplex loading) Operating Conditions 4 - 45 °C, max 80% relative humidity (noncondensing) Solvent Compatibility Typical RP/NP mobile phases, pH range 2.010.0...

 Open the catalog to page 2

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