Clinical Chemistry Anti-CCP Anti-CCP testing in your chemistry workflow

Rheumatoid Arthritis – It’s Never too Early to Test Rheumatoid Arthritis (RA) is a common, systemic autoimmune disease affecting between 0.5-1% of the adult population. It is characterised by inflammation of the synovial joints which can lead to progressive joint destruction and consequent impairment in quality of life. Early intervention is vital in preventing irreversible joint damage and it is therefore important to diagnose RA as early as possible.1 Antibodies to citrullinated proteins/peptides (ACPAs) are reported to be strongly associated with the progression of RA. In the routine clinical...

Anti-CCP antibodies have traditionally been measured by heterogeneous immunoassay -either time-consuming ELISA tests or on closed mainframe immunoassay analysers. The Axis-Shield Clinical Chemistry Anti-CCP assay provides a quick and accurate method for use on most clinical chemistry platforms. For the first time, anti-CCP testing can now be consolidated into your routine chemistry workflow. Assay Performance • Excellent concordance with clinical classification • High specificity for RA • Equivalent performance to established immunoassay methods Simple assay protocol for easy use on most clinical...

Axis-Shield Clinical Chemistry Anti-CCP Assay • Applicable to many different clinical chemistry analysers • Simple direct assay with two reagents and three steps • Consolidate with acute phase reactants and other serology markers into your routine chemistry workflow References 1. Landewe RB, 2003; Arthritis Rhuem; 48:46-53, 2. Van Venrooij et al, 2008; Ann NY Acad Sci;l 143:268-285 3, Pruijn G et al,20l0; Arthritis Res Ther; 12:203 4. Rantappa-Dahlqvist S et al, 2003; Arthritis Rheum;482741 -2749 5. van Gaalen FA et al, 2004; Arthritis Rheum;50:709-715 9. van der Linden MP et al, 2009, Arthritis...