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avance® nerve graft

avance® nerve graft

avance® nerve graft

Product catalog summary
Overview: The document describes a biologically active processed human nerve allograft designed for surgical repair of peripheral nerve discontinuities. It highlights the Avance Nerve Graft and Axoguard product lines, detailing their applications, advantages, and specifications.
Key Advantages:
  • Provides structural support for cellular migration and regenerating axons.
  • Preserves the 3D micro-architecture of native human nerve.
  • Offers an organized, linear, and continuous scaffold.
  • Clinically proven with 82% meaningful recovery in nerve gaps.
  • Eliminates comorbidities and reduces operative time.
  • Supported by over 135 peer-reviewed publications.
The Avance Method™:
  • Preserves native nerve architecture for axon regeneration.
  • Exposes bioactive laminin to promote nerve regeneration.
  • Extensive testing ensures identity, purity, and safety.
Product Specifications:
  • Available in various lengths and diameters (5 mm to 70 mm).
  • Handles, sutures, and flexes like native nerve.
Clinical Applications:
  • 82% meaningful recovery in sensory, mixed, and motor nerve gaps.
  • 95% recovery after neuroma excision and reconstruction.
  • Preferred choice for hand surgeons in digital nerve gaps of 2 cm.
Product Codes and Dimensions: Detailed tables provide specific dimensions for different product codes, catering to various surgical needs.
Regulatory and Indications:
  • Avance Nerve Graft is classified as human tissue for transplantation, adhering to FDA and international regulations.
  • Axoguard products are indicated for specific nerve repair scenarios, with contraindications for porcine sensitivity and certain pathologies.
Contact Information: Axogen Corporation provides contact details for further inquiries and product information.
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Catalog excerpts

avance® nerve graft-1

The only off-the-shelf biologically active processed human nerve allograft intended for the surgical repair of peripheral nerve discontinuities. bioactive laminin-rich endoneurial tubes key advantages Structural support for cellular migration and regenerating axons Preserves the 3-dimensional (3D) microarchitecture of native human nerve Organized, linear, and continuous scaffold across the length of the graft Clinically proven, off-the-shelf solution 82% meaningful recovery in sensory, mixed, and motor nerve gaps in multi-center study1 Eliminates the comorbidities and operative time associated with a second surgical site Over 135 peer-reviewed clinical publications 82% meaningful recovery throughout the body1 The Avance Method™ ensures regenerative potential Preserves the delicate architecture of native nerve to provide structural support for regenerating axons Exposes bioactive laminin known to promote nerve regeneration Extensive testing verifies the identity, purity, and safety of each Avance Nerve Graft lot Intra-operative versatility Available in a variety of lengths and diameters to meet a range of anatomical needs Handles, sutures, and flexes at joints similar to native nerve choice for hand surgeons in digital nerve gaps of 2 cm2 revolutionizing the science of nerve repair™ meaningful recovery after neuroma excision and reconstruction

 Open the catalog to page 1
avance® nerve graft-2

one company for all your surgical nerve repair solutions Biologically active, processed human nerve allograft developed for bridging nerve discontinuities up to 70 mm Semi-translucent coaptation aid for nerve transections up to 5 mm Extracellular matrix that remodels to protect injured nerves and reinforce nerve reconstructions Separates nerve end from surrounding environment to protect from mechanical stimulation and reduce painful neuroma formation references 1. afa B, Jain S, Desai MJ, et al. Peripheral nerve repair throughout the body with processed S nerve allografts: Results from a large...

 Open the catalog to page 2
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