Description Creation Date Product Change Notice Number Revision This Product Change Notice supersedes the following documents: FluidX Xcap Re-launch 22.05.2020 NOC 2012 1.0 N/A 1. Description and Reason for Change Dear Customer, Dear Collaborator, We are pleased to inform you that Brooks Life Sciences is re-launching FluidX Xcap - a semi-automatic system for TPE septum cap sealing of sample tubes in 96-well SBS format. Xcap provides secure storage tube sealing to preserve sample integrity and audit trails in biobanks, compound libraries and other high-throughput storage applications. FluidX Xcap has been on the market for quite some time and continues to be the ideal choice when selecting a TPE septum cap sealer. However, to better fulfill the demands of our target customers and, to stay in line with market expectations and needs, Brooks Life Sciences has decided to invest in the expansion of the Xcap portfolio to better meet the needs of each Sample Management entity. Therefore, BLS has decided to: • simplify the quoting and ordering process; • release new product configurations - two versions of the device have been developed to better address customers across the globe with different electrical requirements and physical connections: - 115V (in general: North and Central Americas, Western Japan) - 230V (in general: the rest of the world, with some exceptions) • add an adapter set for broad compatibility These changes will decrease lead times. This document describes and summarizes all modifications that will impact this product model. All modifications summarized in this NOC will be effective as of June 15th 2020. 2. Communication Distribution – Need to know list Customer’s Procurement Customer’s End User Customer’s Service Team Brooks Life Sciences Service Team Brooks Life Sciences Customer Care Team Sales Managers to inform Sales Managers to inform Sales Managers to inform Product Management to inform Product Management to inform 3. Classification of change Customer Notification Information Only

Xcap is a semi-automatic system for TPE septum cap sealing of sample tubes in 96-well SBS format. Offering secure storage tube sealing, Xcap helps preserve sample integrity and audit trails in biobanks, compound libraries and other high-throughput storage applications. Xcap is suitable for use with all 96-format FluidX sample storage tubes with TPE septum caps and is also compatible with Micronic tubes with TPE Capmats, Matrix Technologies tubes with Sepraseals and Abgene Sealing Mats. The depth of capping action is adjustable with the use of spacer plates, which ensure effective and efficient...

DESCRIPTION Semi-automatic system for TPE septum cap sealing of sample tubes and micro plates in 96-well SBS format (115V) Includes set of adapters: 42-1001; 6.09.661 and 42-1003. Semi-automatic system for TPE septum cap sealing of sample tubes and micro plates in 96-well SBS format (230V) Includes set of adapters: 42-1001; 6.09.661 and 42-1003 As customer expectations are rising faster than ever, Brooks Life Sciences decided to improve the customer experience when working with a FluidX Xcap unit. Associated with faster lead times, these brand-new configurations will now include: • An updated...

It is also important to note that the current packaging solution used on 46-2004 was reviewed and re-designed to not only accommodate the new accessories but also to ensure a safer shipment of the product. Every unit supplied will now follow Brooks serialization strategy for a better customer care and service experience. 4.3 Replacement Products As of June 15th, 2020, Brooks Life Sciences will no longer supply the products listed below. The Part Numbers are being made obsolete as they are duplicate part numbers and unnecessary as part of our product portfolio. Please refer to “Replaced by” column...