BD™ AbSeq antibody-oligo conjugates
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The science you thought of, but couldn’t do. Until now. BD AbSeq antibody-oligo conjugates ™ BD™ AbSeq antibody-oligonucleotides conjugates leverage oligonucleotide sequencing to attain high-parameter protein detection for multi-omic analysis at the single-cell level. This new technology enables researchers to simultaneously detect protein* and mRNA expression in the same experiment. BD AbSeq antibody-oligo conjugates for single cell analysis include BD RhapsodyTM system advantages: • Simultaneously characterize surface proteins and mRNA expression at the single-cell level. Expand your current research capabilities by adding cell-surface protein expression profiling to single-cell mRNA-Seq experiments with next-generation sequencing (NGS) to generate multi-omics data. BD offers a full solution—from upstream labelling of your sample to library preparation, secondary analysis, and data visualization. BD AbSeq antibody-oligo conjugates offer INSIGHT Interrogate high-parameter cell-surface protein markers in a single panel combined with RNA expression. Use the same quality BD clones that you have come to trust from BD Pharmigen™, a leader in antibody quality. Benefit from a comprehensive solution, spanning antibody reagents and single cell capture to bioinformatics and data visualization. Bring in protein expression data to provide better sample characteristics, such as more distinct cell cluster identification, enabling you to more deeply profile cells to further elucidate complex biological systems. • Receive value assurance in a product backed by BD’s reputation for high quality antibodies and cell analysis products. Use one readout to analyze both protein and RNA, reducing experimentation time and increasing information derived from a single experiment. • Get transformative results for diverse fields and applications. • Obtain a digital data readout using molecular barcoding with unique molecular identifiers (UMIs). • Examine cells at a level of detail never before seen. Push the limits of discovery and measure both mRNA and protein expression* for the same single cell.

A. BD Rhapsody targeted mRNA-Seq alone B. BD AbSeq combined with BD Rhapsody targeted mRNA-Seq Cell types B Cells 10 (14.0%) Dendritic Cells (1.6%) Memory CD4 T (14.1%) Memory CD8 T (3.2%) 0 Monocytes (11.3%) NK Cells (12.0%) Naive CD4 T (23.7%) Naive CD8 T (20.1%) -10 B Cells (14. Dendritic Ce Memory CD Memory CD Monocytes NK Cells (1 Naive CD4 Naive CD8 Cell types One readout answers two questions. BD AbSeq enables high-parameter protein expression data simultaneously with single-cell RNA-Seq data to significantly improve your understanding of individual cells and cell populations. BD...