Myeloperoxidase (MPO) enzyme is found in neutrophil primary granules and monocyte lysosomes. MPO catalyzes the conversion of hydrogen peroxide to hypochlorite and hypochlorous acid. MPO is encoded by a single gene that undergoes posttranslational modification to produce the active enzyme found in leukocytes. Autoantibodies to MPO (MPO antineutrophil cytoplasmic antibodies: ANCA) occur in several diseases and may be involved in the pathogenesis of vascular inflammation in patients with microscopic polyangiitis (MPA). Patients with MPA often develop MPO ANCA and may present with azotemia secondary to glomerulonephritis (pauci-immune necrotizing glomerulonephritis). MPO ANCA are not specific for MPA, and also may be detected in patients with systemic lupus erythematosus with or without lupus nephritis, Goodpasture syndrome and Churg-Strauss syndrome. Lupus nephritis and Goodpasture syndrome, as well as Wegener granulomatosis may present with azotemia and progressive renal failure. It is not possible to distinguish among these diseases on the basis of clinical signs and symptoms; autoantibody testing may be helpful. Test cassette Extraction buffer

Specification Sample type Sample vol. Assay time Working range Performance Storage Shelf Life Ordering Information Item Myeloperoxidase (MPO) Test Kit Packing 25 tests/box; 20 boxes/ctn Beijing O&D Biotech Co., Ltd. Web: www.odbio.com Contact: Grace Zhang, [email protected]; Jason Du, [email protected] ADD: West, Floor 4, Building 1, No.1, Shunqiang Road, Renhe Town, Shunyi District, Beijing, Chi

Compatible Instruments Specifications Item KS-001 Dry Fluorescent Immunoassay Analyzer KS-002 Dry Fluorescent Immunoassay Analyzer Catalogue Number Testing Modes Auto-test/Queuing/Instant test Automatic testing Testing Speed 120 T/h under the Queuing Mode 8" LCD screen. The instrument can be connected to a monitor by VGA interface. Built-in thermal printer Built-in thermal printer

Technical Strength 1. Semi-Liquid Phase Reaction Half of the immune reaction is done in the liquid phase, which effectively improves the sensitivity and accuracy of the product. In the sample, the antigen binds more fully to the fluorescently labeled antibody. The release of fluorescent microspheres on the NC membrane is more uniform. Test results of whole blood samples have better repeatability. 2. Red Nanofluorescent Technology a. Comparing with ordinary fluorescein 1) FITC (fluorescein isothiocyanate) and other fluorescent substances are light sensitive and thus easily quenched. Their fluorescence...

O&D Biotech Fluorescent Immunoassay Parameters Sample Test Item Working Range Shelf Life NT-proBNP Cardiac