Pepsinogen I/Pepsinogen Ⅱ (PGI/PGII) Test Kit (FIA) 00032C

Product catalog summary

Introduction
Pepsinogen I and II are precursors of pepsin produced by the gastric mucosa. They are released into the gastric lumen and peripheral circulation. Changes in serum levels of these biomarkers are associated with gastric mucosa inflammation and atrophic gastritis (AG). Pepsinogen II is particularly useful for diagnosing gastritis, as it can differentiate between normal mucosa and gastritis. In acute gastritis, pepsinogen II levels increase, while pepsinogen I levels remain unchanged.

Test Kit Specifications
The Pepsinogen I/II Test Kit is designed for whole blood, serum, or plasma samples with a volume of 75 μL. The assay time is 15 minutes, with a working range of 10-200 ng/mL for PGI and 5-100 ng/mL for PGII. The performance coefficient of variation (CV) is ≤15%. The kit should be stored at temperatures between 2-30℃ and has a shelf life of 18 months.

Ordering Information
The test kit is available under catalog number 00032C, with 25 tests per box and 20 boxes per carton. It is compatible with KS-001 and KS-002 Dry Fluorescent Immunoassay Analyzers.

Compatible Instruments
KS-001 Analyzer: Single-channel, 7" LCD touch screen, built-in thermal printer, dimensions 265x212x128 mm, weight 2.5 kg.
KS-002 Analyzer: 12-channel, 8" LCD screen, VGA interface for monitor connection, built-in thermal printer, dimensions 490x328x336 mm, weight 16 kg.

Technical Strengths
1. Semi-Liquid Phase Reaction: Enhances sensitivity and accuracy by allowing more complete antigen-antibody binding.
2. Red Nanofluorescent Microsphere Technology: Offers stability and resistance to light quenching, maintaining fluorescence efficiency.

Additional Test Parameters
The document also lists various other tests available, including cardiac markers (CK-MB, D-Dimer, CRP, etc.), diabetes markers (HbA1c, Cys-C, etc.), hormone levels (β-HCG), infection markers (PCT, SAA, etc.), and others (S100-β, NGAL, etc.). Each test has specific sample types, volumes, assay times, working ranges, and clinical references.

Contact Information
Beijing O&D Biotech Co., Ltd. provides the test kits. Contact persons include Grace Zhang and Jason Du, with contact details provided for further inquiries.

Catalog excerpts

Pepsinogen I/Pepsinogen Ⅱ (PGI/PGII) Test Kit (FIA) 00032C-1

Pepsinogen I and II, the precursors of pepsin, are produced by the gastric mucosa and released into the gastric lumen and peripheral circulation (Samloff and Liebman, 1973). Severe inflammation of gastric mucosa and its progression toward atrophic gastritis (AG) is correlated with a change in serum biomarkers pepsinogen I and II. It has been previously reported that pepsinogen II is a good marker for the diagnosis of any type of gastritis as it can differentiate between subjects with gastritis from those with normal mucosa. The progression of gastritis to acute and pangastritis is associated with a continual increase in serum pepsinogen II levels, whereas the levels of pepsinogen I in the early stage of acute gastritis remain unchanged and in the normal range. Test cassette Extraction buffer

Open the catalog to page 1

Pepsinogen I/Pepsinogen Ⅱ (PGI/PGII) Test Kit (FIA) 00032C-2

Specification Sample type Sample vol. Assay time Working range Performance Storage Shelf Life Ordering Information Item Pepsinogen I/Pepsinogen Ⅱ (PGI/PGII) Test Kit Packing 25 tests/box; 20 boxes/ctn Beijing O&D Biotech Co., Ltd. Web: www.odbio.com Contact: Grace Zhang, [email protected]; Jason Du, [email protected] ADD: West, Floor 4, Building 1, No.1, Shunqiang Road, Renhe Town, Shunyi District, Beijing, C

Open the catalog to page 2

Pepsinogen I/Pepsinogen Ⅱ (PGI/PGII) Test Kit (FIA) 00032C-3

Compatible Instruments Specifications Item KS-001 Dry Fluorescent Immunoassay Analyzer KS-002 Dry Fluorescent Immunoassay Analyzer Catalogue Number Testing Modes Auto-test/Queuing/Instant test Automatic testing Testing Speed 120 T/h under the Queuing Mode 8" LCD screen. The instrument can be connected to a monitor by VGA interface. Built-in thermal printer Built-in thermal printer

Open the catalog to page 3

Pepsinogen I/Pepsinogen Ⅱ (PGI/PGII) Test Kit (FIA) 00032C-4

Technical Strength 1. Semi-Liquid Phase Reaction Half of the immune reaction is done in the liquid phase, which effectively improves the sensitivity and accuracy of the product. In the sample, the antigen binds more fully to the fluorescently labeled antibody. The release of fluorescent microspheres on the NC membrane is more uniform. Test results of whole blood samples have better repeatability. 2. Red Nanofluorescent Technology a. Comparing with ordinary fluorescein 1) FITC (fluorescein isothiocyanate) and other fluorescent substances are light sensitive and thus easily quenched. Their fluorescence...

Open the catalog to page 4