is the first and only fully adaptive AID system

iLet Bionic Pancreas The new standard in AID systems. The iLet Bionic Pancreas is the first and only fully adaptive AID system. The most advanced system available. Most adaptive A fully adaptive system dynamically and autonomously adapts all underlying insulin dosing parameters.1 What is the difference between a fully adaptive AID system and a static AID system? FULLY ADAPTIVE No other system autonomously delivers 100% of insulin doses. Closest to a fully closed loop system Three algorithms that dynamically adapt between appointments Rigid insulin settings locked in until the next appointment...

Real-world evidence Two years of real-world evidence showed that adults and children who switched to the iLet achieved a 1.6% improvement in HbA1c to GMI.2 Great results. Period. Adults: 1.5% improvement Pediatrics: 1.9% improvement Average Change Average GMI on the iLet Sample size = 16,394 iLet users In the pivotal study: The iLet achieved dramatic increases in TIR from baseline3

iLet algorithms have it covered. The iLet makes 100% of the insulin dosing decisions, so your patients don’t have to. A day in the life with the dosing intelligence of the iLet Bionic Pancreas Tiffani’s iLet delivers the right basal doses throughout the day, adjusting every 5 minutes to her changing needs The iLet senses this and delivers correction insulin Tiffani had a light snack and her glucose starts to rise slightly Tiffani sits down to eat lunch and chooses “Usual for me” for her meal announcement. Having learned what “usual” carbs are for her at lunch time, the iLet determines the right...

Three independent algorithms work together to deliver great outcomes. BASAL ALGORITHM • Autonomously determines basal insulin needs • Adapts basal insulin dosing every 5 minutes CORRECTIONS ALGORITHM • • Automatically kicks in when glucose levels start to rise—no calculations needed from the user Autonomously brings the user’s glucose levels back down, adjusting correction doses every 5 minutes MEAL ANNOUNCEMENT ALGORITHM • • No carb counting*—only qualitative meal announcements are required. The iLet then determines the prandial dose autonomously. Learns and adapts to the user’s mealtime behavior...

What people love about their iLet. Most study participants found the iLet to be better or much better than their previous AID system.4 No complicated carb counting* at mealtime Autonomous, real-time correction doses Real-time, personalized care for constantly changing insulin needs Reduces diabetes distress and anxiety among adults and caregivers5 Can be used with Humalog, Novolog, or prefilled Fiasp PumpCart cartridges * User must be carb aware. Connects to Dexcom CGMs or FreeStyle Libre 3 Plus sensor Bionic Circle App The Bionic Circle App helps caregivers take the guesswork out of managing...

The iLet has great pharmacy coverage Most iLet users who go through pharmacy benefits pay $0 for the pump and no more than $25/month for supplies. • Faster access • Reduced out-of-pocket costs • No 4-year pump commitment Prescribe the iLet on Parachute. We’re here 24x7 to support you and your patients. Call 1-855-745-3800 and choose option 1. Talk with your next patient about the benefits of the iLet Bionic Pancreas today! iLet Simulator betabionics.com References 1 Cook, K., et.al (2025). Defining the Automated Insulin Delivery Continuum: User Engagement and System Adaptation. ADCES 2025. Poster...