CoolSink

CoolSink

Product catalog summary
Introduction
BioCision, LLC presents a solution to the problem of non-uniform plate cooling when using crushed ice. The document discusses the CoolSink® thermo-conductive plate modules designed to provide uniform temperature distribution across all wells of a plate.

Problem Statement
The document identifies the issue of non-uniform cooling in a 96-well flat bottom plate when in direct contact with crushed ice. This results in uneven well temperatures, which can affect experimental outcomes.

Solution: CoolSink® Technology
The CoolSink® thermo-conductive plate modules are introduced as a solution. These modules ensure uniform temperature distribution by rapidly adapting to the temperature of the source, ranging from -196°C to over +100°C. They are compatible with various temperature sources such as ice, dry ice, liquid nitrogen, and water baths. The modules can be autoclaved, sterilized, or decontaminated with common lab disinfectants.

Product Specifications
  • CoolSink XT 96F: Designed for 6-, 12-, 24-, 48-, 96-, or 384-well flat bottom plates. Dimensions: 12.8 x 8.5 x 1.7 cm.
  • CoolSink XT 96U: Designed for 96-well u-bottom plates. Dimensions: 12.8 x 8.5 x 1.7 cm.
  • CoolSink LX55: For 55 mL reagent reservoirs. Dimensions: 14.6 x 6.4 x 3.5 cm.


Performance and Benefits
When using the CoolSink module, the plate shows uniform well-to-well temperature, with all wells reaching or staying below 4°C. This uniformity is crucial for consistent experimental results. The document highlights that the center wells may be slightly warmer due to the plate's curvature.

Conclusion
The CoolSink® modules provide a reliable solution for achieving uniform temperature distribution in laboratory settings, enhancing the accuracy and reliability of experimental results.
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Catalog excerpts

CoolSink-1

Thermo-Conductive Plate Modules CoolSink thermo-conductive plate and reservoir modules provide uniform temperature to all wells, regardless of position. When placed onto a temperature source such as ice, dry ice, liquid nitrogen or water baths, the CoolSink module will rapidly adapt to that temperature - from -196°C to >+100°C. CoolSink modules ensure temperature sample uniformity when cooling, snap freezing, heating or thawing samples. All CoolSink modules may be autoclaved, high heat sterilized or decontaminated with bleach, alcohol or other disinfectants or lab detergents. All modules are compatible with all temperature sources. Problem: Non-Uniform Plate Cooling with Crushed Ice Final equilibrium well temperature for a 96-well flat bottom plate in direct contact with crushed ice. Solution: Uniform Plate Cooling with CoolSink XT 96F Module CoolSink 96F on ice. Colors represent 0.5°C temperature intervals of the corresponding plate wells. The white cell represents the well that was fitted with the thermocouple probe. Plate directly on crushed ice does not reach 4°C in any of the wells and well-to-well temperature is uneven. Plate placed on CoolSink module and then placed on ice shows more uniform well-to-well temperature and all wells at or below 4°C (Blue center plate wells are slightly warmer due to curvature of the underside of the plate.) Published in Biotechniques, November 2010. Plate and Reservoir Modules CoolSink® XT SBS-compatible plate modules Item No. BCS-536 For Use With For one 6-, 12-, 24-, 48-, 96- or 384-well flat bottom plate For one 96-well u-bottom plate CoolSink® LX55 For 55 mL reagent reservoirs Dimensions (L x W x H) 12.8 x 8.5 x 1.7 cm BioCision, LLC 101 Glacier Point Road, Suite E, San Rafael, CA 94901 USA [email protected] www.biocision.com © 2015. BioCision, LLC. All rights reserved. Patents pending. BioCision, CoolSink designations are trademarks owned by BioCision, LLC. PN 2

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