RTS-8, Multi-channel Bioreactor with non-invasive real time cell concentration measurement
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RTS-8, Multi-channel Bioreactor with non-invasive real time cell concentration measurement - 1

Biosan SIA., Ratsupites 7, build. 2, Riga, LV-1067, Latvia, Phone: +371 674 261 37, Fax: +371 674 281 01, E-mail: marketing@biosan.lv, www.biosan.lv RTS-8, Multi-channel Bioreactor with non-invasive real time cell concentration measurement DESCRIPTION RTS-8 is a personal bioreactor that utilizes patented Reverse-Spin® technology that applies non-invasive, mechanically driven, low energy consumption, innovative type of agitation where cell suspension is mixed by the single-use falcon bioreactor tube rotation around its axis with a change of direction of rotation motion resulting in highly efficient mixing and oxygenation for aerobic cultivation. Combined with a near-infrared optical system it is possible to register cell growth kinetics non-invasively in real time. FEATURES Parallel cultivation of 8 tube bioreactors enables to save time and resources for bioprocess optimization Individually controlled bioreactor accelerates optimization process Possibility to cultivate microaerophilic and obligate anaerobic microorganisms (not strict anaerobic conditions) Reverse–Spin® mixing principle enables non-invasive biomass measurement in real time Near-infrared optical system makes it possible to register cell growth kinetics Free of charge software for storage, demonstration and analysis of data in real time Compact design with low profile and small footprint for personal application Individual temperature control for bioprocess applications Active cooling for rapid temperature control, e.g. for temperature fluctuation experiments Task profiling for process automatization Cloud data storage to remotely monitor the process of cultivation while at home or using a mobile phone SOFTWARE FEATURES Real–Time cell growth logging 3D graphical representation of OD or growth rate over time over unit Pause option Save/Load option Report option: PDF and Excel Remote monitoring option (requires internet connection) Cycling/Profiling options User manual calibration possibility for most cells CAT. NUMBER Including TPP TubeSpin® Bioreactor vessels 50ml, 20pcs BS-010168-A01 TYPICAL APPLICATIONS Fermentation real time growth kinetics Clone candidate screening Protein expression Temperature stress and fluctuation experiments Media screening and optimization Growth characterization Inhibition and toxicity tests Strain quality control Initial bioprocess optimization studies RTS-8, Multi-channel Bioreactor with non-invasive real time cell concentration measurement

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RTS-8, Multi-channel Bioreactor with non-invasive real time cell concentration measurement - 2

SPECIFICATIONS Light source Measurement range E.coli factory calibration measurement range S.cerevisiae factory calibration measurement range Achievable user calibration measurement error (range 0.1-6 OD600) Achievable user calibration measurement error (range 6-50 OD600) Achievable user calibration measurement error (range 50-75 OD600) Measurement periodicity per hour Temperature setting range Temperature control range Temperature stability Sample temperature accuracy (20°C – 37°C) Tube sockets Sample working volume range Speed control range Reverse spin time setting range 150-250 rpm...

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