ACTIVITY, MOTOR CONTROL & COORDINATION • SPONTANEOUS PAIN - POSTURAL DEFICIT • PAIN - THERMAL ALLODYNIA / HYPERALGESIA • PAIN - MECHANICAL ALLODYNIA / HYPERALGESIA • ANXIETY & DEPRESSION DISORDER • LEARNING - MEMORY - ATTENTION - ADDICTION • PHARMACOLOGY & PHYSIOLOGICAL PARAMETERS • SURGERY & STEREOTAXY EQUIPMENT • METABOLISM A QUICK & EASY ASSESSMENT DEVICE FOR THE MECHANICAL NOCICEPTIVE THRESHOLD OF BIG MAMMALS BIO-VETALGO Big Mammals Analgesimeter INSTRUMENT OVERVIEW Bioseb’s Vetalgo is simple to operate: a force-gauge display is equipped to an external stimulator. The assembly is mounted on an ergonomic handle, that fits both left-handed and right-handed investigators. The type of stimulator is to be chosen according to the application surface and the type of nociceptive stimulus to be applied. After placing the animal on a secured position, a progressive force is applied by the investigator on the area of interest, until a response from the animal is noticed: deliberate escape movement away from the device, vocalization, attempts to bite or to scratch the instrument, turning the look at the testing site, etc. Both maximum and current pressure values are shown in real-time on the large display. The MNT (Mechanical Nociceptive Threshold) value is the value at which the animal reacts, being the Max. value of Pressure application, in the standard steadily increasing procedure. The measurement is accomplished using a highly accurate sensor of 5000g Max. Capacity and an electronic device offering a sampling rate of 1000 Hz, which ensures that the maximum force is perfectly captured and displayed, even for short and low force peaks – allowing test of a wide range of animal’s pain sensitivity. Bioseb’s Vetalgo is a new pressure-based analgesimeter designed for big mammals. Delivered with 3 different-size stimulators, the profile of mechanical stimulus & the application surface fit various animals (horses, cats, dogs, pigs, sheep, calves) and testing sites: joints, vertebras, pelvic area, hoof, wound, soft tissue, muscle, horn, metatarsus, carpal pad, etc. Von Frey filaments are commonly used to quantify pain or assess sensory sensitivity, but are time-consuming and do not avoid crosscontamination - moreover, it is limited to 300g of force. The large capacity of our Pressure Algometer, 5000g, allows mechanical nociceptive threshold measurement for most big mammals. Veterinary studies, such as “Briley J.D et al. Feasibility and repeatability of cold & mechanical quantitative sensory testing in normal dogs. The Veterinary Journal (2013)“ show the importance of quantitative sensory testing (QST) to evaluate pain threshold in mammals with OA inflammation, pelvic pain or muscle-related troubles. The Vetalgo’s repeatability & validity have been demonstrated and it is recommended as part of a multimodal, complete somatosensory evaluation set: a must in veterinary’s standard equipment for the improvement of animal’s life quality. KEY FEATURES • Objective, immediate reading of MNT (up to 50 N) • Repeatable & reliable values over time • Ergonomic handle (left/right-handed operators) • Robust design for use in animal housing • No cross-contamination: delivered with disposable plastic tips and cleanable steel tips Supplied with 3 different probes The Vetalgo fits various animals (horses, cats, dogs, pigs, sheep, calves) and testing sites: joints, vertebras, pelvic area, hoof, wound, soft tissue, muscle, horn, metatarsus, carpal pad, etc. Phone: North America +1 727 521 1808 - Europe & other Areas +33 442 344 36

BIO-VETALGO: Bioseb’s Pressure Algometer for Big Mammals DEDICATED SOFTWARE An embedded statistical computation has been included in the electronic device. This is a very useful feature that has been very well received by researchers, especially when a large number of tests is required. The display shows in real time the mean, standard deviation and variation coefficient from groups of animals. The optional BIO-CIS software sends data acquired via the Pressure Algometer into an MS Excel spreadsheet using the RS232 port and USB converter. Easy to set up, this soft interface also allows the display...