1. Catalogs
  2. Bioseb
  3. STUDIES ON ANXIETY & DEPRESSION

STUDIES ON ANXIETY & DEPRESSION

STUDIES ON ANXIETY & DEPRESSION

STUDIES ON ANXIETY & DEPRESSION

Product catalog summary
Overview: The document discusses innovative research instruments for studying anxiety and depression, focusing on the Tail Suspension Test (TST) and the Forced Swimming Test (FST). These tests evaluate antidepressant efficacy and behavioral responses in mice and rats.
Main Instruments:
  • Tail Suspension Test (TST): A fully automatic, wireless system measuring immobility in mice to indicate depressive-like states. It uses strain gauges and video recording for accurate, operator-independent results.
  • Forced Swimming Test (FST): Also known as the Porsolt Test, this dual-sensor system uses vibration detection and video analysis to assess drug effects. It is suitable for both mice and rats, allowing simultaneous testing of up to four animals.
  • Elevated Plus Maze: A test for anxiety-related behaviors, though details are limited in the document.
Technical Specifications:
  • TST: Measures up to 6 mice per run, uses Bluetooth connectivity, and provides data on immobility, energy, and power in motion.
  • FST: Utilizes the TYC algorithm for consistent scoring, supports video replay, and offers detailed analysis of swimming, immobility, and struggling behaviors.
Applications: These instruments are used for drug screening, studying behavioral abnormalities, evaluating antidepressant efficacy, and understanding the effects of genetic manipulations and pharmacological compounds on mood disorders.
Software Features: The dedicated software for both TST and FST allows easy setup, data export, and replay of experiments. It supports randomization, threshold adjustments, and GLP-compatible data protection.
Ordering Information: The document provides details on hardware, power requirements, and dimensions for setting up the tests, along with contact information for ordering and further inquiries.
Instrument Overview: The Elevated-Plus-Maze (EPM) is used in neurobiological research to assess anxiety-like behavior in rodents. It evaluates the efficacy of anxiolytic and anxiogenic drugs using rodents' natural aversion to heights and open spaces. Bioseb offers a comprehensive solution for the EPM test, including hardware and software components. The EPM-3C software automates the test using video tracking, aligning with manual scoring through specific morphologic detection.
How It Works: The EPM consists of a plus-shaped apparatus with two open and two enclosed arms, elevated from the floor. Rodents' anxiety is measured by the time spent in closed versus open arms. The test lasts about 5 minutes, with data recorded on time spent in each arm, number of entries, total distance traveled, and latency to first entry into an open arm. Results can be exported to Excel for further analysis.
Technical Specifications: The EPM system includes color tracking technology, real-time analysis from camera flow or video files, and an HD USB camera with a resolution of 744x480 pixels and a sampling rate of 76 fps. The maze dimensions vary for mice and rats, and the equipment is lightweight and easy to assemble.
Domains of Application: The EPM is used for prescreening pharmacological agents for anxiety-related disorders, studying anxiolytic and anxiogenic effects, and examining the impact of stressors and aging on anxiety. It also serves as a behavioral assay to study brain sites and mechanisms underlying anxiety behavior.
Parameters Measured: The software measures total time per zone, latency to first entry, number of visits, distance covered, mean time per visit, and mean speed. These parameters indicate anxiety and locomotor activity in test subjects.
See more

Catalog excerpts

STUDIES ON ANXIETY & DEPRESSION-1

ACTIVITY, MOTOR CONTROL & COORDINATION • SPONTANEOUS PAIN - POSTURAL DEFICIT • PAIN - THERMAL ALLODYNIA / HYPERALGESIA • PAIN - MECHANICAL ALLODYNIA / HYPERALGESIA • ANXIETY & DEPRESSION DISORDER • LEARNING - MEMORY - ATTENTION - ADDICTION • PHARMACOLOGY & PHYSIOLOGICAL PARAMETERS • SURGERY & STEREOTAXY EQUIPMENT • METABOLISM MEETING YOUR NEEDS BY DESIGNING INNOVATIVE AND HIGH-QUALITY SOLUTIONS FOR YOUR RESEARCH STUDIES ON ANXIETY & DEPRESSION MAIN INSTRUMENTS • Tail Suspension Test • Automated Forced Swimming Test • Elevated Plus Maze Phone: North America +1 727 521 1808 - Europe & other Areas +33 442 344 360 - Email: info@bioseb

 Open the catalog to page 1
STUDIES ON ANXIETY & DEPRESSION-2

ACTIVITY, MOTOR CONTROL & COORDINATION • SPONTANEOUS PAIN - POSTURAL DEFICIT • PAIN - THERMAL ALLODYNIA / HYPERALGESIA • PAIN - MECHANICAL ALLODYNIA / HYPERALGESIA • ANXIETY & DEPRESSION DISORDER • LEARNING - MEMORY - ATTENTION - ADDICTION • PHARMACOLOGY & PHYSIOLOGICAL PARAMETERS • SURGERY & STEREOTAXY EQUIPMENT • METABOLISM THE ONLY FULLY AUTOMATIC SOLUTION IN THE WORLD FOR RUNNING A SIMPLE AND OBJECTIVE DESPAIR TEST ON MICE Tail Suspension Test INSTRUMENT OVERVIEW HOW DOES IT WORK? The TST is based on strain gauges measuring the quantity of movement generated by a mouse trying to escape from...

 Open the catalog to page 2
STUDIES ON ANXIETY & DEPRESSION-3

BIO-TST5: Tail Suspension Test - Wireless - Automatic DEDICATED SOFTWARE The brand new software for Bioseb's Tail Suspension test is based on direct acquisition from the strain sensors, as well as video monitoring. It is powerful, yet flexible and user-friendly. • Just one screen is needed to set up all parameters: number of animals, thresholds, starting/ending times of the measuring period. • The animal list can be edited, exported, or imported from Excel or CSV format directly. • The «Randomization» module defines the order of the different «dosed» animals with their groups. • During the test,...

 Open the catalog to page 3
STUDIES ON ANXIETY & DEPRESSION-4

ACTIVITY, MOTOR CONTROL & COORDINATION • SPONTANEOUS PAIN - POSTURAL DEFICIT • PAIN - THERMAL ALLODYNIA / HYPERALGESIA • PAIN - MECHANICAL ALLODYNIA / HYPERALGESIA • ANXIETY & DEPRESSION DISORDER • LEARNING - MEMORY - ATTENTION - ADDICTION • PHARMACOLOGY & PHYSIOLOGICAL PARAMETERS • SURGERY & STEREOTAXY EQUIPMENT • METABOLISM A VERY INNOVATIVE AND EASY TO USE INSTRUMENT FOR BOTH MICE OR RATS - COMPLETELY OPERATOR-INDEPENDENT BIO-FST: Dual-Sensor Forced Swimming Test INSTRUMENT OVERVIEW The Forced Swimming Test (FST), also known as Porsolt Test or “behavioral despair test”, is a common behavioral...

 Open the catalog to page 4
STUDIES ON ANXIETY & DEPRESSION-5

BIO-FST: Dual-Sensor Forced Swimming TestDEDICATED SOFTWARE Bioseb's Forced Swimming Test FST DUAL SENSOR solution allows automatic computing of several parameters or states for rats and mice: • Non-active (immobility, passive floating) • Dipping (rat only: can be easily set manually when analysing the files) Results are organized by groups or individual animal, and can be displayed for every minute of the test. or by time period. Acquisition can be replayed and re-analyzed with different settings: a calibration made by an expert from another lab can also be used. The scoring tool is useful for...

 Open the catalog to page 5
STUDIES ON ANXIETY & DEPRESSION-6

ACTIVITY, MOTOR CONTROL & COORDINATION • SPONTANEOUS PAIN - POSTURAL DEFICIT • PAIN - THERMAL ALLODYNIA / HYPERALGESIA • PAIN - MECHANICAL ALLODYNIA / HYPERALGESIA • ANXIETY & DEPRESSION DISORDER • LEARNING - MEMORY - ATTENTION - ADDICTION • PHARMACOLOGY & PHYSIOLOGICAL PARAMETERS • SURGERY & STEREOTAXY EQUIPMENT • METABOLISM A COMPLETE, DEDICATED & AUTOMATED SOLUTION FOR THE ELEVATED-PLUS OR ZERO MAZE TEST BIO-EPM3C Elevated-Plus-Maze INSTRUMENT OVERVIEW The Elevated-Plus-Maze is a common test to assess anxiety-like behavior in laboratory animals. Based on the natural fear of rodents for height...

 Open the catalog to page 6
STUDIES ON ANXIETY & DEPRESSION-7

BIO-EPM3C: Elevated-Plus-Maze System: 3 clicks only! DEDICATED SOFTWARE The Bioseb EPM-3C Software gives all the information you need from your EPM experiment and most of the parameters are computed in real-time. The data is available for each arm individually, but also for grouped arms. The results can be exported to windows Excel - the software runs under Windows Seven and Eight. Following table introduces the results available with the Bioseb software and the scientific meaning of each data. Bioseb's epmsc software: Total time per zones (s and %) Main indicator to assess anxiety Latency to...

 Open the catalog to page 7

All Bioseb catalogs and technical brochures

  1. SWB

    2  Pages

  2. DWB

    2  Pages

  3. BIO-CH

    2  Pages

*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.
About MedicalExpo
MedicalExpo is a marketplace that offers B2B players a complete experience, from product sourcing to purchase. MedicalExpo is an entity of VirtualExpo Group.