CytoCentric Products • Full Time O2/CO2 Optimization During Handling • Full Time Protection • Better Cell Growth • Better Cell Health • Maximum User Comfort • Ample Workspace • Accommodates Subchambers O2 and CO2 (optional) Optimized Glove Box CYTOCENTRIC HOOD The C-Shuttle is part of a practical system for handling your cells under the same conditions at which they incubate. It provides ample workspace where you can handle and manipulate your cells without disruption of O2 and/or CO2. FULL TIME OPTIMIZATION DURING CELL HANDLING Interruption in optimal O2 and/or CO2 conditions can have major effects on cell cultures. Normally when cells are manipulated outside their incubator in clean hoods, controlled gases such as CO2 and O2 are disrupted. Cells are brought into the C-Shuttle via sub chamber. The buffer chamber matches the workspace environment, then cells are accessed from the interior door. Effects can be devastating on cultures. Consider oxygen regulated genes. Hypoxia upregulated genes are immediately shut off by even brief exposures to room air. Imagine what can happen to receptors, ion channels, cytokines, extracellular matrix, etc. when the pH changes out of the physiologic range! DOCKS SUBCHAMBERS FROM REMOTE INCUBATORS Using a transport vessel such as the BioSpherix C-Chamber between the C-Shuttle and your incubator is the most economical way to achieve uninterrupted conditions. The incubator protects cells from exposure. The transport chamber maintains conditions for the brief period between controlled environments. The C-Shuttle is controlled, and the buffer chamber allows your cells to enter without disrupting the set environment wi

Installation Schematic The unique C-Shuttle is comprised of several components to complete a system. It provides a workspace for cell cultures under the same O2/CO2 conditions where the cells reside within the incubator. Another component, the C-Chambers, provide a semisealed gas-controlled transport mechanism for cultures to travel from the incubator, to the glove box, and back to the incubator. The buffer chamber of the glove box is designed to fit C-Chambers. You can leave a C-Chamber in the buffer chamber, remove cells into uninterrupted O2/ CO2 atmosphere, manipulate them without disturbance,...

C-SHUTTLES PROTECT THE RESEARCHERS Cells are often purposely grown and processed to generate or test viruses and vectors. More worrisome is when cells are unknowingly infected with viruses or other transmissible agents. The C-Shuttle limits exposure to harmful viruses, vectors and prions where conventional open labs allow the technicians to breathe potentially dangerous non-cellular biological entities. UNINTERRUPTIBILITY When working in a C-Shuttle your cells are never exposed to sub-optimal conditions. Whether you’re using O2/CO2/N2/CO your workspace and transport is always controlled to a...

Typical configuration for one user access (Top view) COMPLETE SYSTEM - The C-Shuttle, a C-Chamber (sold separately), a gas controller (system comes with ProOx P360, other options available) and gas (customer supplied). A nitrogen gas supply is necessary for hypoxia. If CO2 control is necessary, a CO2 controller and tank of CO2 is also required. Optional two user access configuration (Top view) Dimensions CONTROLLERS - Controllers such as the ProOx P360 (pictured above) and similar O2 / CO2 controllers fit the C-Shuttle. They are flexible and very capable. Three standard C-Chambers sizes are compatible...