CELL RESEARCH PRODUCTS

Cells Need Full Time Protection . . . Not Part Time Cells outside the body no longer have an immune system to protect them from microbes. Conventional equipment provides only part-time protection. Cytocentric-by-design equipment provides full time protection. Cytocentric upgrade options for conventional equipment can increase protection, even up to full time. Cells Need Full Time Optimization . . . Not Part Time Cells outside the body no longer have the body to keep them viable. Temperature, pH, osmolarity, O2, CO2, etc. must be controlled at optimal levels outside the body or cells die. Conventional...

What is Cytocentric? It is a new and better way to grow and manipulate cells in vitro. It goes beyond the needs of people, to meet the needs of cells. You might say Cytocentric is a philosophy, and in some ways it is. It certainly includes an unusually hefty reverence for cells. But in reality, our new approach to cell culture and processing is based on a lot of hard science, much of which is brand new and currently unfolding in hundreds of labs around the world. In another way, our new approach is simply a more disciplined and strict approach based on old knowledge about cells. Somehow, this...

XVIVO INCUBATION SYSTEM model FIRST CELL INCUBATION SYSTEM ACTUALLY DESIGNED FOR CELLS INSTEAD OF PEOPLE …CYTOCENTRIC BY DESIGN Cells need more than conventional incubators provide. This cutting edge incubation technology is the first that can satisfy those needs. More than a typical incubator, it is a comprehensive system of modular interconnecting incubation chambers, sub-chambers, and co-chambers with advanced controls. Modules can be fitted together like building blocks, and configured for virtually any application, large or small. If needs change, you can easily modify and upgrade your incubator...

... If Your Cells Need Their Own Protocol Unlike conventional incubators with one chamber and one protocol, the X3 has the option of multiple independent chambers per incubator. Each can have different conditions simultaneously. That means different culture protocols can run in one incubator at the same time. The Xvivo Incubation System can culture up to 15 different protocols in one integrated system! Don’t be fooled by conventional incubators with multiple doors on the same chamber. It is still one protocol. Xvivo incubators can be configured with one large, two medium, or three small incubation...

Any 3rd party cell equipment can be integrated inside, including microscopes (shown above), centrifuges, cell sorters, refrigerators, etc. Regardless of how many independent incubation chambers are integrated into the same processing chamber, all with different conditions, that processing chamber can replicate the unique conditions of that incubator before it is opened. Optimum conditions are never interrupted, regardless of how numerous and varied they might be. Even conventional CO2 incubators can be integrated inside X3 processing chambers, effectively converting people-centric CO2 incubator...

Cells Need Physiologic Simulation Compared to conventional CO2 incubators with oxygen fixed at 20%, the Xvivo System has full range oxygen control (0.1 - 99.9%) in every incubation chamber, and in every processing chamber. Simulating physiologic O2 and simulating pathophysiologic hypoxia or hyperoxia is easy. And the newly recognized critical requirement for preventing oxygen fluctuations during handling is built in. No other system can compare when it comes to oxygen. Cells Need to Protect Their Caretakers Cells incubated and handled in a closed system reduce the risk of transmitting infectious...

Upgrading Conventional Incubators With Cytocentric Features Cells outside the body have needs that cannot be met by conventional incubators and hoods. Rethinking the relationship between incubator and hood led to the Xvivo System which essentially combines the two into one seamless system. Better for cells in every way, Cytocentric by design is likely to be the equipment of choice when the cells are valuable or the research is important. However, it is also possible for any lab to meet any particular need of cells by simply upgrading conventional incubators. Our practical and powerful new line...

Cells can safely be moved into and out of I-Glove inside subchambers and transport chambers without disturbance to O2 and CO2, or exposure to microbes in lab. Incubator Glove Box The I-Glove is a cytocentric accessory for substantially upgrading conventional incubators with full time O2/CO2 optimization, full time protection, physiologic simulation, and accountability. Your incubator is installed inside, immersed in an aseptic O2/CO2 optimized atmosphere. When cells are removed from the incubator and handled inside the I-Glove, there is no change in O2 or CO2. There is also no danger of contamination...

^ Optimal Conditions O2 ^ CO2 C-Shuttle Glove Box The C-Shuttle Glove Box is the most basic and economical option for handling cells under controlled O2 and/or CO2. Cells can be “shuttled” back and forth to this glove box from remote incubators inside closed subchambers without disturbing O2 and/or CO2. Once inside a C-Shuttle Glove Box with identical O2 and/or CO2 concentrations, the subchamber is opened and cells removed and handled with no disturbance in O2 and/or CO2. Cells are then put back inside the subchamber and shuttled back to the host incubator for incubation, for full time optimization. •...

• Extends the range of user protocols within the user’s incubator • Full time protection • Optimized for gas efficiency • Saves gas in comparison to an incubator • Magnetic door control - no latches • Prevents cross-contamination • Quick recovery after access to cells • No complicated “flushing” procedures • Four standard sizes Cells inside a subchamber are not disrupted by the opening of the host incubator. Options Subchambers can be functionalized by any variety of controllers according to protocol size and needs. • One Shelf • Two Shelf • Three Shelf • Four Shelf