The bone substitutes in the Activabone® line act as collagenated osteoconductives and bone promoters with total osteoclastic remodeling, mixed with polymer carrier with modulated visco-elasticity and used as grafts in bone regeneration procedures. Surgical Advantages Leaching withstand ability and easier handling - Bone pastes based on first generation carriers (standard), often feature rheological properties unsuited to assure good handling or to withstand leaching during grafting in a bloody environment. Perfect adaptability: a graft for any defect. By suitably modifying the dose of Vitamin C (viscomodulating), it is possible to obtain extremely versatile and functional bone substitutes, having specific biological properties, texture, malleability and adhesiveness, such as to adapt perfectly to the specific geometry of the bone defects of any dimension or shape. Production and R&D Center: Via G. Agnelli, 3 - 10020 Riva presso Chieri (Turin) - Italy Bioteck® is an Italian company producing bone substitutes and protective membranes successfully used in orthopaedics, neurosurgery, oral and maxillofacial surgery. Founded in 1995, the company continues to grow constantly and now operates in more than 50 countries around the world. A firm commitment to scientific research forms the basis for the innovative solutions offered by Bioteck® products. The company collaborates on numerous national and international research projects, which have driven basic research and helped in writing important chapters in bone biology. The in-depth knowledge acquired by Bioteck® through its research ensures the absolute quality of its products, which are subjected to strict environmental and quality controls, thereby guaranteeing they the highest quality and safety standards. Bioteck® applies a policy of total transparency, opening up the doors of its Production and R&D Center for the monitoring of its innovative process and the intense scientific research carried out by its staff. The new generation of bone pastes concept: mauro forlani - vi Bioteck S.p.A. Headquarters: Via E. Fermi 49 - 36057 Arcugnano (Vicenza) - Italy Tel. +39 0444 289366 - fax: +39 0444 285272 [email protected] - www.bioteck.com Optimal dissolution Persists at the grafting site for the time required for tissue regeneration to occur. Enhanced osteopromotion Thanks to the optimal proliferation of cells within the threedimensional structure of the polymeric carrier and, in some formats, strongly implemented by the presence of DBM. In over twenty years of scientific research and clinical practice, Bioteck® has given an important contribution to the clinical/scientific knowledge in the field of tissue biology. The Bioteck Academy is the meeting place of all the excellences that continuously contribute to the development of this knowledge. The Academy has developed a culture of sharing scientific knowledge aimed at the dissemination of best techniques and practices in the various areas of regenerative surgery and is open to all professionals who decide to participate in this activity by sharing their surgical experience. More information on the activities of the Academy can be found at: www.bioteckacademy.com. Perfect adaptability The wide range of available visco-elasticity makes it easy to find the right product for any type of defect. Clinical Advantages Optimal regeneration - The total remodeling biomaterial is combined with a polymer carrier that further enhances its regenerative power: while maintaining stability and spaces, it actively stimulates the formation of new bone tissue. 2 1 - Formation of immature (fibrous) bone tissue due to use of quickly dissolving bone pastes. 2 - Perfectly regenerated bone tissue thanks to the use of Activabone® pastes. Notice the presence of the already perfectly developed marrow component. New generation visco-modulated bone pastes orthopae

The new generation of bone pastes Packed with technology The line of Activabone® bone pastes stems from a unique technological combination. The equine origin bone substitutes obtained through the exclusive Zymo‑Teck® enzymatic process are now associated to Exur®, the innovative polymer carrier with modulated viscosity developed by Bioteck R&D. ACTIVABONE® CRUNCH Composition: demineralized bone matrix (DBM), Exur (low molecular weight carrier (LMW), Vitamin C). Applications: osteopromoter to be mixed with grafts for filling bone defects, including non contained ones. Applied on the surfaces of...

The bone substitutes in the Activabone® line act as collagenated osteoconductives and bone promoters with total osteoclastic remodeling, mixed with polymer carrier with modulated visco-elasticity and used as grafts in bone regeneration procedures. Surgical Advantages Leaching withstand ability and easier handling - Bone pastes based on first generation carriers (standard), often feature rheological properties unsuited to assure good handling or to withstand leaching during grafting in a bloody environment. Perfect adaptability: a graft for any defect. By suitably modifying the dose of Vitamin...

The new generation of bone pastes Packed with technology The line of Activabone® bone pastes stems from a unique technological combination. The equine origin bone substitutes obtained through the exclusive Zymo‑Teck® enzymatic process are now associated to Exur®, the innovative polymer carrier with modulated viscosity developed by Bioteck R&D. ACTIVABONE® CRUNCH Composition: demineralized bone matrix (DBM), Exur (low molecular weight carrier (LMW), Vitamin C). Applications: osteopromoter to be mixed with grafts for filling bone defects, including non contained ones. Applied on the surfaces of...

The new generation of bone pastes Packed with technology The line of Activabone® bone pastes stems from a unique technological combination. The equine origin bone substitutes obtained through the exclusive Zymo‑Teck® enzymatic process are now associated to Exur®, the innovative polymer carrier with modulated viscosity developed by Bioteck R&D. ACTIVABONE® CRUNCH Composition: demineralized bone matrix (DBM), Exur (low molecular weight carrier (LMW), Vitamin C). Applications: osteopromoter to be mixed with grafts for filling bone defects, including non contained ones. Applied on the surfaces of...