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Product catalog summary

Introduction
The document discusses the MeRG, a Type-1 collagen bi-layer membrane derived from equine Achilles tendon, used for guided cartilage regeneration, particularly in treating focal cartilaginous lesions using the Steadman microfracture technique.

Eligibility Criteria
Patients eligible for this treatment are those with Grade III and IV focal cartilage lesions according to Outbridge, with defect sizes over 2 cm² and depths up to 5-6 mm. The age range for patients is 18-55 years.

Exclusion Criteria
Exclusions include hypersensitivity to collagen, related cartilaginous defects (kissing lesions), hemophilia, and systemic diseases such as infections and osteoarthritis.

Collagen Patch Features
The MeRG membrane acts as a biological chamber, locking mesenchymal cells in situ and boosting regeneration with a supercoagule. It consists of two membranes for better adhesion and protection.

Surgical Applications
The application involves debridement of the chondral lesion, dry shaping, hydration with physiological or biological fluids for cell enrichment, deployment on the lesion post-microperforation, and fixation with fibrin glue.

Post-Operative Treatment
For 1-6 weeks, patients should use light touch-down weight bearing with crutches and continuous passive motion from 0° to 90°. From the 6th week, gradual weight bearing is advised, progressing to full weight bearing over the next two weeks.

Product Range
The MeRG product range includes various sizes of BIOCOLLAGEN MeRG Membranes, including standard and soft membranes.

References
The document cites several studies and reviews related to the clinical application of bone marrow aspirate in orthopedics and cartilage regeneration techniques.

Catalog excerpts

Collagen Membrane for Guided Cartilage Regeneration

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Treatment of focal cartilaginous lesions using Steadman microfracture technique. MeRG is a Type-1 collagen bi-layer membrane obtained from equine Achilles tendon Biological Chamber Lock in the mesenchymal cells in situ Boosting regeneration 2 Membranes in 1 Better adhesion & protection ELIGIBILITY Grade III and IV focal lesions of the cartilage according to Outbridge (involvement of the subchondral bone), defect size in excess of 2 cm2, depth of defect up to 5-6 mm. Patient age: 18-55 yrs. EXCLUSION CRITERA Hypersensitivity to collagen, related cartilaginous defects (kissing lesions), hemophilia,...

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SURGICAL APPLICATIONS Techniques 1 Mini-Arthrotomy 2 Arthroscopy-CO2 MeRG at work - Quick Reference 1 Debridement of chondral lesion 2 Dry shaping, hydration with physiological or with biological fluids for cell enrichment (PRP, Bone Marrow Concentrate) for 2-3 minutes. 3 Membrane is deployed on the lesion following its microperforation. 4 MeRG is fixated by applying fibrin glue on the edges. Smooth side Rough side Cartilage Microfracturing Hole MSCs Subchondral Bone The application of MeRG® and the sealing of the biological chamber PRODUCT BIBLIOGRAPHY 1. Gianakos, A.L., et al., Clinical application...

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MeRG Product Range BCG-merg BIOCOLLAGEN MeRG Membrane BCG-mergK/Q BIOCOLLAGEN MeRG Membrane BCG-mergS BIOCOLLAGEN MeRG Soft Membrane Bioteck S.p.A. Headquarters: Via E. Fermi 49 - 36057 Arcugnano (Vicenza) - Italy Tel. +39 0444 289366 - fax: +39 0444 285272 [email protected] - www.bioteck.com Production and R&D Center: Via G. Agnelli, 3 - 10020 Riva presso Chieri (Turin) - Italy Collagen Membrane -1 pc. 50 x 50 x 0.2 mm. Collagen Membrane -1 pc. 30 x 30 x 0.2 mm. Collagen Soft Membrane -1 pc. 50 x 50 x 0.4 mm.

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Catalog excerpts

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