PHERAstar FSX
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The gold standard for high-throughput screening BMG ' LRBTGCH The Microplate Reader Company

Your benefits at a glance: · Best sensitivity and speed in all assays · Steady temperature unaffected by external changes · Assay Optic Modules for easiest optical configuration · Automation friendly · High temporal resolution in TR-FRET detection · Optimisation tool for TRF/TR-FRET and AlphaScreen · Cross-talk reduction for AlphaScreen and luminescence · Made-in-Germany dependability The best performance in all assays Developed to fulfil the hardest High-Throughput Screening The PHERAstar FSX combines the fast read times necessary (HTS) requirements, the PHERAstar® FSX high-end micro- for...

Four photomultiplier tubes, combined in two application by cutting read times in half and eliminates the typical dedicated matched pairs, are used as detectors. One pair is drawbacks of double sequential detection such as flash- dedicated to simultaneous dual fluorescence and to-flash variations, photobleaching and decaying kinetic luminescence detection, the second to TRF-based signals. signals. SDE also reduces the variability caused by fluctuations in pH or temperature, and by evaporation. Switch between assays in seconds Ultra-fast detection of absorbance spectra Never worry about which...

Cross-talk reduction Without aperture With aperture AlphaScreen/AlphaLISA and glow luminescence assays in 384- and 1536-well plates in particular are often negatively affected by stray light and cross-talk. Unwanted light may diffuse from adjacent wells to the detector, as well as through the plastic walls of the wells. If cross-talk is not reduced, low-signal wells might see more counts from nearby bright wells than from their actual signal. BMG LABTECH's cross-talk reduction package automatically applies an aperture to physically reduce non-specific signals diffusing from nearby wells,...

Advanced Well Scanning Conventional readers excite and measure samples in the centre of the well. This can negatively affect data quality when measuring uneven cell layers or non-homogenous well samples. On the PHERAstar FSX, three different well scan modes enable robust data acquisition even from non-homogeneous samples such as adherent cells or bacteria. Orbital and spiral averaging automatically normalise for heterogeneous cell distributions. In these modes, the reader takes several measurements on a defined orbit and calculates an average for each well, For higher resolution, matrix...

Data analysis made easy The software package includes the Reader Control and MARS data analysis interfaces. This multi-user software can be installed on as many computers as you require, without the need to purchase additional licenses. The Reader Control software allows to define measurement protocols and acquire data. It is an extremely versatile interface for the straightforward execution of routine tasks, as well as the optimisation of complex operations. MARS is designed to make data analysis simple and effective, and offers multiple data reduction possibilities such as: · Standard...

■ DNA, RNA, and protein quantification ■ Enzyme activity and kinetic assays ■ Cell-based assays ■ And much more ... Our comprehensive online application database reflects more than 30 years of expertise and innovations. Over 8,000 published entries of peer-reviewed articles and application notes demonstrate the flexibility and versatility of our readers, and their use in chemical and biological sciences. Automation The PHERAstar FSX offers excellent robotic integration capabilities, multi-user control, digital signature and FDA 21 CFR part 11 compliance. Its robotic software interface make...

The PHERAstar FSX can include all or any combination of features/options/accessories listed below at purchase. Upgrading with additional features/options/accessories may be possible after purchase. Contact your local representative for more details or a quote. Detection modes Measurement modes Microplate formats Microplate carrier Light sources Wavelength selection Optical path Z-adjustment Spectral range Read times Reagent injection Shaking Integrated barcode reader Incubation Stacker THERMOstar LVis Plate Upgrades UV/vis absorbance Fluorescence intensity - incl. FRET Luminescence (flash...