ESTM10 is an all-in-one system with built-in functions often used in biological imaging experiments and electrophysiology experiments, such as stimulus pulse output, acquisition timing control for camera, lighting control for LED light sources, biological signal recording, and digital oscilloscope, etc. All built-in functions work in sync, so you can connect your peripherals to ESTM10 and have them fully synchronized without any special programming or hardware knowledge. Multifunctional despite its small body. With this one unit, you can handle everything from student training in physiology to academic research. 3. Analog signal recording *2) 4. Digital signal recording 5. Camera frame sync signal input/output LED light source signal output in synchronization with TTL signal input/output 7. Light source signal input/output at any timing 8. Digital oscilloscope 9. Sound monitor output *3) Supports multiple trigger sources (external 10. TTL signal, button, external analog signal, software, internal repeat trigger) Powered by USB connection, operation and 11. pulse settings are programmable from software *1) If necessary, Isolator is sold separately *2) Amplifier is sold separately *3) Speaker with amplifier is sold separately. Areas of Application 1. Electrophysiology experiments using brain/neurons or isolated heart and cultured cardiomyocytes 2. Physiology student practical training using animal samples such as frogs 3. GCaMP imaging for in vivo brain 4. Voltage imaging and calcium imaging using neuronal and cardiac samples Developed by Brainvision Inc. Distributed by SciMedia Ltd. Tokyo, Japan California, USA www.scimedia.com [email protected]

Example of Use Multi-device synchronization Electrical stimulation Perform imaging and electrical signal recording in synchronization with camera, light sources, isolator, and electrophysiological amplifier Stimulate sample in combination with an isolator This device can generate 8 channels of independent pulse trains in any pattern. An example of an experimental setup combining an electrical recording with a recording electrode, electrical stimulation with a stimulation electrode, and 3-wavelength excitation fluorescence imaging that alternately switches 3 color LED light sources in synchronization...