HELBO® PHOTODYNAMIC THERAPY THERAPEUTIC SUCCESS GENTLE AND SECURE

Key to long-term dental and implant preservation and general health

HELBO laser therapy EFFICIENT Anti-microbial photodynamic therapy (aPDT) destroys pathogenic bacteria in oral dysbiosis, helping the body restore physiological equilibrium. Low-level laser therapy (LLLT) reduces pain and also stimulates the body’s own regeneration processes to heal wounds and inhibit inflammation. GENTLE The therapy is pain-free and has no side effects as the low-energy HELBO TheraLite laser does not heat the tissue. Based on CE-certified products and decades of market-leading experience in dental medicine, HELBO therapy delivers safe, effective treatment through an optimally...

Oral biofilm management as a holistic regulation therapy Oral dysbiosis poses a risk for the entire organism. DISEASES IN THE MOUT Gingivitis and mucositis Periodontitis and peri-implantitis Alveolar osteitis Residual osteitis and bone necrosis Endodontitis Caries Skin/mucous membrane disease POOR ORAL HEALTH LEA Cardiovascular diseases Strokes (Chronic) lung diseases Type II diabetes Rheumatoid arthritis Osteoporosis Chronic kidney failure Chronic intestinal diseases Cancer (prostate, intestine, pancreas) Premature birth with low birth weight Erectile dysfunction Depression Alzheimer’s

The aim is to restore physiological equilibrium through efficient biofilm management

Reduces prescription of antibiotics, painkillers and anti-inflammatory drugs Effective against a wide range of microorganisms The dye solution stains bacteria, viruses, yeasts, protozoa and their toxins selectively but not the body’s own cells, so that it does not cause tissue damage. The ideal prerequisite for · reducing the risk of infection · mitigating inflammation · fast, complication-free healing CONTROLS INFLAMMATION REDUCES PAIN PROMOTES WOUND HEALING Assisted by low-level laser therapy (LLLT) The effects of low-energy, red laser light on non-dyed body‘s own cells have been shown to produce...

HELBO – convincing mode of action No resistances, no side effects and no interactions Minimally invasive therapy - maximum patient benefit Effect of anti-microbial photodynamic therapy (aPDT): Interaction of a dye solution with light and oxygen. A high-dose, light-sensitive dye solution (photosensitizer) excited with light of a suitable wavelength and dosage produces aggressive oxygen molecules, which destroy bacteria, even deep within the biofilm. Light-sensitive photosensitizer Selective attachment of the light-sensitive photosensitizer to the bacterial wall Light exposure and excitation of...

HELBO – an indispensable companion ... Demonstrated improvement Prof. Dr Andreas Braun Aachen, Germany “A reliable anti-microbial treatment for many years, photodynamics has become firmly established among available laser applications and therefore also used in our clinic. Given the global problem of antibiotic resistance, the use of antibiotics as an adjunct treatment should be limited to strict indications. In many cases, photodynamic therapy offers a local anti-microbial alternative which studies have shown to improve conventional treatment methods.” Reliable results Dr Andriana Barylyak Lviv,...

... and a must-have for my everyday work. Long-term clinical benefits “HELBO is an invaluable tool that I use in almost all areas of dentistry when decontamination and optimised working conditions are required to improve oral health. For instance, HELBO helps with my surgical regenerative treatments for peri-implantitis because it delivers long-term clinical benefits.“ Dr Dragana Rakašević Belgrade, Serbia Prof. Dr Ralf Rössler DTMD, Luxembourg “The risk of resistance is clearly present with systemic antibiotics, which are still routinely used in periodontal care. This makes diseased teeth and...

HELBO aPDT – clinical procedure Helpful adjuvant for customary mechanical cleaning or reprocessing RINSE to remove the excess dye 4. LEAVE TO ACT to allow photosensitizer diffusion (e.g. into biofilm)

Mechanical removal of hard and soft deposits APPLY Apply the photosensitizer to the problem area (e.g. deep periodontal/peri-implant pockets) Indication-specific applications: In our manual, you will find detailed application protocols for the wide range of applications.

Safe, gentle and efficient Advantages for dentists: • Minimally invasive patient treatment; avoids using antibiotics • Sterile products, also suitable for use in surgery • Innovative treatment • Can be delegated; private treatment service (e.g. in Germany) • Simple, fast and safe to use • Compatible with active dental ingredients and regenerative materials • Wavelength of 660 nm: Photobiomodulation without thermal effects included • Laser class 2: no laser protection officer required in the practice • Clinical success, scientifically proven • Pain-free treatment • No antibiotics, no side effects/interactions...

Skin & mucous membrane diseases 26 - 27 Endodontics & deep caries 24 - 25 Alveolar Management/ implantology 20 - 23 Oral surgical indications 18 - 19 Outstanding therapy successes for an impressively wide variety of indications Case studies Periodontal & peri-implant diseases 14 - 17

Periodontal & peri-implant diseases One fifth of all teeth & dental implants worldwide are at risk HELBO is part of the solution Implants BIOFILM/ PLAQUE Gingivitis Mild & moderate periodontitis Severe periodontitis Peri-implant mucositis INFLAMMATION: BOP+ REDNESS ULCERATION CHRONIC INFLAMMATION GUM RECESSION POCKET DEEPENING BONE LOSS TOOTH/ IMPLANT LOSS Percentage of adults (>15 years) with severe periodontal disease: Global oral health status report. WHO, Geneva 2022; ISBN 978-92-4-006148-4. Percentage of patients with peri-implantitis: Lee C. T. et al. J Dent, 2017; 62:1-12.

S Even in aggressive forms of this common disease and in diabetics SEspecially for probing depths > 4 mm and bleeding on probing SFor both closed and open periodontitis therapy. Applied locally, HELBO aPDT ensures any pathogenic bacteria remaining after curettage are killed, thus leading to restoration of a healthy symbiosis. Periodontal & peri-implant diseases Taken from HELBO periodontitis studies: Al-Waeli H.A. et al. Lasers Med Sci, 2015;30(2):801-7. Arweiler, N.B. et al. Clin Oral Investig, 2014; 18(9)2129-35. Chondros, P. et al. Lasers Med Sci, 2009; 24(5):681-8. Martins S. H. L. et al....