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MALDI Biotyper CA System

MALDI Biotyper CA System
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MALDI Biotyper CA System

Product catalog summary
Overview: The document provides a comprehensive overview of the MALDI Biotyper CA System, a mass spectrometry-based technology for identifying microorganisms in clinical microbiology. It emphasizes the system's accuracy, speed, cost-effectiveness, and user-friendliness.
Key Features:
  • Technology: Employs MALDI-TOF mass spectrometry to identify microorganisms by their unique proteomic fingerprint.
  • Accuracy: Offers reliability comparable to nucleic acid sequencing.
  • Speed: Capable of approximately 200 identifications per hour, surpassing traditional methods.
  • Cost-Effectiveness: Provides a cost-efficient solution for microbial identification.
  • Ease of Use: Designed for simplicity, requiring no prior mass spectrometry experience, with a straightforward workflow and user-friendly software.
System Components:
  • Includes the microflex LT/SH mass spectrometer, a desktop computer, and dedicated software.
  • Requires minimal space and operates with low noise and heat output.
Operational Workflow:
  • Involves selecting an isolated colony, transferring the sample, adding a matrix, and generating a MALDI-TOF spectrum.
  • The software matches the spectrum against a reference library, providing results in a traffic light color scheme for easy interpretation.
Data Analysis:
  • Utilizes a biostatistical algorithm to compare the test organism's spectrum with reference spectra, calculating a log(score) value for identification accuracy.
  • A log(score) value of ≥ 2.00 indicates a high probability of accurate identification at the species level.
Library and Algorithm:
  • The reference library is developed with Main Spectra (MSP) based on multiple measurements to capture biological variability.
  • An advanced algorithm ensures high accuracy and reproducibility through statistical multi-variant analysis.
Intended Use: The system is intended for identifying microorganisms cultured from human specimens, aiding in the diagnosis of bacterial and yeast infections.
Conclusion: The MALDI Biotyper CA System is a robust, compact, and high-performance platform designed for routine use in microbiology laboratories, offering enhanced performance and productivity.
Microorganisms Identified: The document lists various microorganisms including Streptococcus gordonii, Streptococcus intermedius, Streptococcus lutetiensis, Streptococcus mutans, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus salivarius, Streptococcus mitis oralis group, Sutterella wadsworthensis, Trichosporon asahii, Vibrio parahaemolyticus, Vibrio vulnificus, Yersinia enterocolitica, and Yersinia pseudotuberculosis.
MBT CA System Consumables: The document describes consumables for the MALDI Biotyper CA System, which include:
  • US IVD Bacterial Test Standard (BTS): An E.coli extract spiked with high molecular weight proteins for quality control, covering the entire mass range of proteins used by the system. It includes one box with 5 tubes, each providing approximately 40 spots (Part No 604530).
  • US IVD HCCA Matrix: A matrix for easy preparation of HCCA matrix solutions, soluble in standard organic solvents, stable, and enables sensitive measurements. It includes one box with 10 tubes, each providing approximately 250 samples (Part No 604531).
  • US IVD 48 Spot Target: A reusable polished steel target with a barcode for MALDI-TOF-MS, providing 48 sample spots and supporting full traceability in paperless workflows (Part No 604532).
Notes: The document notes that Bruker Daltonics is continually improving its products and reserves the right to change specifications without notice. The MALDI Biotyper® is a registered trademark of Bruker Daltonik GmbH in the EU and USA.
Contact Information: Bruker Daltonics Inc., Billerica, MA, USA. Phone: +1 (978) 663-3660, Fax: +1 (978) 667-5993, Email: [email protected], Website: www.bruker.com
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Catalog excerpts

MALDI Biotyper CA System-1

Achromobacter xylosoxidans Acinetobacter lwoffii Acinetobacter radioresistens Acinetobacter ursingii Ac netobacter baumannii complex Acinetobacter baumannii Acinetobacter calcoaceticus Acinetobacter noso mialis Acinetobacter pittii Actinomyces oris Aeromonas sp Aeromonas allosaccharophila Aeromonas cav Aeromonas culicicola Aeromonas hydrophila Aeromonas ichthiosmia Aeromonas veronii Aeromonas sobr Alcaligenes faecalis Bacteroides_ovatus group Burkholderia gladioli Burkholderia multivorans Burkholder cepacia complex Burkholderia ambifaria Burkholderia anthina Burkholderia cenocepacia Burkholderia cep Burkholderia diffusa Burkholderia dolosa Burkholderia lata Burkholderia latens Burkholderia metallica Bur eria pyrrocinia Burkholderia seminalis Burkholderia stabilis Burkholderia vietnamiensis Candida dublinien Candida glabrata Citrobacter amalonaticus complex Citrobacter amalonaticus Citrobacter farmeri Citrobac freundii complex Citrobacter braakii Citrobacter freundii Citrobacter gillenii Citrobacter murliniae Citrobac werkmanii Citrobacter youngae Citrobacter rodentium Citrobacter sedlakii Citrobacter koseri Corynebacte bovis Corynebacterium amycolatum Delftia_acidovorans group Eikenella corrodens Enterobacter aerogen terobacter cloacae complex Enterobacter asburiae Enterobacter cancerogenus Enterobacter cloacae Enter ter hormaechei Enterobacter kobei Enterobacter ludwigii Enterococcus gallinarum Escherichia coli Finego magna Geotrichum capitatum Haemophilus haemolyticus Haemophilus influenzae Haemophilus parainflu zae Hafnia alvei Klebsiella pneumoniae Klebsiella_oxytoca / Raoultella_ornithinolytica Kingella kingae Koc kristinae Moraxella_sg_Branhamella catarrhalis Moraxella_sg_Moraxella osloensis Morganella morganii P toea agglomerans Parabacteroides distasonis Parabacteroides distasonis Pasteurella multocida Pediococc pentosaceus Propionibacterium acnes Proteus mirabilis Proteus vulgaris group Proteus hauseri Proteus pe Proteus vulgaris Providencia rettgeri Providencia stuartii Pseudomonas aeruginosa Pseudomonas fluoresc group Pseudomonas oryzihabitans Pseudomonas azotoformans Pseudomonas brenneri Pseudomonas ce Pseudomonas congelans Pseudomonas corrugata Pseudomonas extremorientalis Pseudomonas fluoresc Pseudomonas gessardii Pseudomonas libanensis Pseudomonas mandelii Pseudomonas marginalis Pseud nas migulae Pseudomonas mucidolens Pseudomonas orientalis Pseudomonas poae Pseudomonas rhodes Pseudomonas synxantha Pseudomonas tolaasii Pseudomonas trivialis Pseudomonas veronii Pseudomona putida group Pseudomonas fulva Pseudomonas monteilii Pseudomonas mosselii Pseudomonas plecoglos Pseudomonas putida Rothia dentocariosa Rothia mucilaginosa Salmonella sp Salmonella enterica ssp ariz Salmonella enterica ssp bongori Salmonella enterica ssp diarizonae Salmonella enterica ssp enterica Salm la enterica ssp houtenae Salmonella enterica ssp indica Salmonella enterica ssp salamae Serratia rubidae ratia liquefaciens Serratia marcescens Stenotrophomonas maltophilia Streptococcus agalactiae Streptoco anginosus Streptococcus constellatus Streptococcus dysgalactiae Streptococcus gallolyticus Streptococc gordonii Trichosporon asahii Vibrio parahaemolyticus Vibrio vulnificus Yersinia enterocolitica Yersinia pse MALDI Biotyper CA System Clinical Application for Identification of Microorganisms Innovation with Integrity

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MALDI Biotyper CA System-2

In Microbiology, Speed and Accuracy Matters The MALDI Biotyper CA System A powerful technology for better results Identifying microorganisms by their molecular ngerprint To help answer key challenges in Clinical Microbiology, Bruker has utilized its many years of experience to create the truly groundbreaking MALDI Biotyper CA System. With its combination of performance and utility, the MALDI Biotyper CA System is revolutionizing the way laboratories are performing microbial identifications for clinically significant gram negative bacteria, gram positive bacteria and yeast in the clinical microbiology...

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MALDI Biotyper CA System-3

A Simple Procedure for a Sophisticated Platform Innovative design leads to enhanced performance and productivity The MALDI Biotyper CA System workflow has been designed to be as robust and easy to perform as possible. No previous experience with mass spectrometry is required. The fully traceable workflow has been streamlined and requires only a few simple steps to generate high quality microorganism identifications as shown below. Typically no more than an isolated single colony from a culture is required. The entire process needs only a few minutes to complete. Our dedicated microbiology software...

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MALDI Biotyper CA System-4

Easy to Use Software that is In just a few steps, the simple-to-use software guides users through the set-up of Automatic Calibration and Quality Control Check Description: Urine Bench Test Organism definition. The MALDI Biotyper CA System microflex LT/SH mass spectrometer is automatically checked using US IVD BTS (Bacterial Test Standard) before each use. When the check is successful, the system automatically begins the measurement process. Clear identification results display at species level Test Organism Label Organism Identification Escherichia coli Escherichia coli Escherichia coli Enterobacter...

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MALDI Biotyper CA System-5

Rigorous and Sophisticated Data Analysis Assures Accuracy Meaning of score values The spectrum of the unknown test organism, acquired through the MALDI Biotyper CA System Software, is elec- tronically transformed into the peak list. Using a biostatistical algorithm, this peak list is compared to reference peak lists of organisms in the reference library and a log(score) value between 0.00 and 3.00 The higher the log(score) value, the higher the degree of similarity to a given organism in the reference FDA-cleared library. A log(score) value of > 2.00 can be considered an excellent probability...

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MALDI Biotyper CA System-6

The Best Technology from the Experts in Mass Spectrometry As the leader in MALDI-TOF technology, it is of great importance to Bruker to design a robust, compact, high performance platform intended for extensive and routine use in the microbiology laboratory.The core of the MALDI Biotyper CA system is the cutting-edge microflex LT/SH MALDI-TOF mass spectrometer. A true bench-top solution A low-noise operating system with low weight of approximately185 lbs and requiring less than 3 feet of counter space offers flexibility in meeting laboratory needs for compact systemsolutions. The MALDI Biotyper...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.