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Bruker Daltonics Inc.
MBT Mycobacteria Library

MBT Mycobacteria Library

Product catalog summary

Introduction
The document discusses the advancements in Bruker Daltonics' MALDI Biotyper® Mycobacteria Library, focusing on the identification and differentiation of Mycobacterium species, which include significant pathogens like the Mycobacterium tuberculosis complex (MTC) and nontuberculous mycobacteria (NTM).

Library Expansion
The Mycobacteria Library 3.0 has been significantly expanded to include over 850 reference entries, with more than 400 clinical isolates, enhancing the differentiation capabilities among Mycobacterium species.

Extraction Protocol
Bruker has developed the MycoEX protocol, a silica bead-based extraction method that provides high-quality mass spectra for species identification, overcoming the limitations of traditional methods.

Media Compatibility
The MycoEX protocol is effective for Mycobacteria grown on both solid Löwenstein-Jensen and liquid BACTEC™ MGIT™ media, showing no significant differences in mass spectra quality.

International Consortium
An international consortium of 24 laboratories across 9 countries has contributed to the library, providing well-characterized clinical isolates that improve strain coverage for clinical analyses.

Species Coverage
The library includes entries for a wide range of Mycobacterium species, enhancing the ability to identify and differentiate between various strains.

Usage Note
The Mycobacteria Library is intended for research use only and not for diagnostic procedures.

Catalog excerpts

Mycobacteria Library MALDI Biotyper ® Innovation with Integrity

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The genus Mycobacterium includes, as major groups, the important pathogens of the Mycobacterium tuberculosis complex (MTC) and the nontuberculous mycobacteria (NTM). Members of the latter group are cited increasingly as the cause for opportunistic infections among immuno-compromised patients. This trend and the rise of antibiotic resistance in this genus demand improved differentiation among Mycobacteria species. The Mycobacteria Library 3.0 is a major step forward in Bruker’s commitment to cover the natural variability of Mycobacterium species. Hundreds of new reference strains have been added...

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One workflow for solid media and liquid cultures Mass Spectra of Mycobacterium peregrinum DSM 43271 T Spectra of Mycobacteria grown on solid Löwenstein-Jensen or BACTEC™ MGIT™ (BD Diagnostics) liquid media show no significant differences. Figure 2: Mass Spectra of Mycobacterium peregrinum DSM 43271T cultivated on Löwenstein-Jensen medium (top) and in MGIT™ tube (bottom), using the MycoEX protocol. International mycobacteria consortium The aim of this consortium is to collect securely identified Mycobacteria strains for the creation of a high quality spectrum library. Twenty-four laboratories...

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Mycobacteria Library 149 species entries in Mycobacteria Library M. hassiacum M. abscessus subsp. bolletii M. avium subsp. avium M. avium subsp. paratuberculosis M. avium subsp. silvaticum M. fortuitum subsp. acetamidolyticum M. fortuitum subsp. fortuitum MALDI Biotyper® is a registered trademark of Bruker Daltonik GmbH in the European Union and USA. For research use only. Not for use in diagnostic procedures. Bruker Daltonik GmbH Bremen · Germany Phone +49 (0)421-2205-0 Fax +49 (0)421-2205-103 [email protected] - www.bruker.com to change specifications without notice. © BDAL 04-2015,...

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