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XLIMUS®

Product catalog summary

Introduction
The document introduces the XLIMUS, a revolutionary biodegradable drug-eluting stent system designed to treat complex coronary lesions. It highlights the use of Sirolimus-eluting cobalt chromium technology, emphasizing its unmatched deliverability and performance in treating coronary artery disease.

Specifications
The XLIMUS stent system features a thin stent strut design with a thickness of 73µm, including a 2µm coating layer. It is made from a cobalt chromium alloy (L-605) and offers a wide range of stent sizes, from 2.25 mm to 5.00 mm in diameter and lengths from 8 mm to 40 mm. The system is compatible with 5F and 6F guiding catheters and a 0.014" guidewire.

Design and Performance
The stent system is designed for optimal flexibility and stability, featuring a 6-8-10 cell design that ensures even vessel wall coverage without flaring or open gaps. The stent's architecture minimizes trauma and restenosis, providing homogenous vessel wall scaffolding. The innovative hydrophilic-coated shaft and low tip profile enhance tracking performance, allowing access to tortuous lesions.

Drug Elution and Biodegradability
XLIMUS employs a biodegradable polymer for controlled Sirolimus drug release, ensuring rapid endothelial healing and effective inhibition of smooth muscle cell proliferation. Approximately 70% of the drug is released within 30 days, with sustained efficacy up to 120 days. This controlled release reduces inflammation and the risk of late restenosis.

Clinical Efficacy
The stent system provides clinically effective antiproliferative drug delivery, optimizing protection against tissue prolapse and ensuring long-term patient safety. The document references the COMPARE trial, highlighting the low metal volume of XLIMUS compared to other stents, which enhances stability.

Conclusion
XLIMUS represents a significant advancement in coronary stenting technology, offering a comprehensive solution for complex coronary lesions with its innovative design, effective drug delivery, and patient safety features.

Catalog excerpts

A REVOLUTIONARY STENT SYSTEM to treat complex coronary lesions biodegradable drug elution Sirolimus-eluting cobalt chromium coronary stent technology.

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deliverability and XLIMUS performance. The most innovative Sirolimuseluting cobalt chromium coronary stent technology available.

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Leading the future of drug-eluting coronary stenting. • XLIMUS is the ultimate coronary DES stent system to treat complex coronary artery disease by reaching and crossing the most challenging lesions. • XLIMUS offers a stable, flexible stent delivery system featuring a flexible tip technology allowing navigating the most tortous coronary anatomies. • XLIMUS is a next generation thin stent strut Sirolimus DES, using the No. 1 drug which demonstrated long-term patient safety and optimal clinical efficacy, in more than 10.0 Million Patien

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optimized thin stent strut design homogenous vessel wall scaffolding The outstanding XLIMUS 6-8-10 stent cell design. 10 cells 8 cells 6 cells Ensures even vessel wall coverage. Any different artery lesion diameter ranging from 2.25 up to 5.00mm is stented evenly. Homogenous deployment distribution: Surface A1 = A2 = A3

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No stent flaring. No tissue prolapse. Clinically effective. Homogenous, clinically effective drug delivery optimizes the anti-proliferative protection of the stented lesion segment. No stent strut flaring. No open gaps. The technically high standard of 6-8-10 intermediate and closed-cell stent architecture covers all vessel diameters evenly. XLIMUS quality ensures the best possible intracoronary stenting stability and minimizes stenting trauma and restenosis. Extraordinary homogenous vessel wall scaffolding. XLIMUS assists the cardiologist with an optimal, unsurpassed tracking performance. It...

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XLIMUS drug-coating technology. A novel drug-eluting, cobalt chromium coronary stent system, which provides clinically effective antiproliferative, drug delivery to the coronary artery lesion to prevent restenosis, followed by a rapid functional endothelial healing. Biodegradable Polymer Sirolimus Drug Elution Following the nature. Stent flexibility by design. Pulse Synchronous Stent Dynamics respond to coronary artery movement, with every heart beat. Natural stent flexion minimizes friction and shear stress to avoid vessel wall trauma. For a lifetime patient safety! Controlled biodegradable...

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Life deserves the best. XLIMUS ensures a controlled drug release after stent implantation. XLIMUS controlled biodegradable Sirolimus drug release.

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The widest range of 72 stent sizes. Stent Diameter (mm) *upon request, no lead time available Technical Data Cobalt Chromium Alloy L-605 Total strut thickness 73µm (71µm Alloy + 2µm coating layer) Coating layer Device lengths Stent length = balloon length = markers distance Metal to artery ratio Nominal pressure Rated burst pressure 16 ATM except diameters 4.5 / 5.0 and diameter 4.0 with length higher than 20mm (14 ATM) Average foreshortening Guiding catheter compatibility Guidewire compatibility Sirolimus (Rapamycin) drug-coating International Sales Office and Legal Manufacturer CARDIONOVUM...

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XLIMUS®

XLIMUS®

Catalog excerpts

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