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Intra-operative Frozen-Section-pathology diagnostic IHC Products -CELNOVTE

Intra-operative Frozen-Section-pathology diagnostic IHC Products -CELNOVTE

Intra-operative Frozen-Section-pathology diagnostic IHC Products -CELNOVTE

Product catalog summary
Overview: The document provides detailed information on intra-operative frozen-section immunohistochemistry (IHC) products and procedures offered by Celnovte Bio-Tech. It highlights the use of PolyStackerTM detection polymer technology to enhance sensitivity and reduce turnaround time to 10 minutes.
Background: Traditional H&E staining is the standard for intra-operative consultations but has limitations due to ice crystal artifacts affecting tissue morphology. This can lead to misdiagnosis, especially in cases of microlesions. The document references a 2019 report from China indicating a mismatch between intra-operative H&E and post-procedure FFPE IHC results.
Clinical Significance: The IHC products aim to improve diagnostic accuracy by rapidly detecting tumor markers, reducing false negatives, and enhancing match rates with post-operative FFPE IHC results. This assists in better surgical decision-making.
Protocol: The IHC procedure involves a series of steps: Blocking (20 seconds), Primary Antibody application (4 minutes), Detection (3 minutes), Chromogen application (90 seconds), and Counterstaining (10 seconds).
Core Advantages: The document emphasizes the superiority of their 2-step detection method over competitors' 1-step method. Key advantages include:
  • Higher sensitivity and signal intensity with minimal background.
  • Ready-to-use primary antibodies for frozen section IHC.
  • A specially designed fixative for consistent morphology.
  • A proprietary wash buffer for shorter wash cycles and cleaner backgrounds.
  • PolyStackerTM technology for specific attachment and excellent cellular penetration.
  • Quality control slides for reliable results.
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Catalog excerpts

Intra-operative Frozen-Section-pathology diagnostic IHC Products -CELNOVTE-1

Intra-operative Frozen-Section IHC Products Email: [email protected] Website: celnovte-bio-tech.com

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Intra-operative Frozen-Section-pathology diagnostic IHC Products -CELNOVTE-2

Catalog Name Species Rmab Mmab Mmab Rmab Mmab Mmab Mmab Mmab Mmab Mmab Rmab Mmab Mmab Mmab The unique PolyStackerTM detection polymer technology pushes the sensitivity of poly-HRPAb based detection system to its limit, thus drastically reduce the turnaround time of frozensection IHC experiment to as short as 10mins. Mmab Mmab Mmab Mmab Currently, H&E stain is still the gold standard for intra-operative frozen section consultation. Nevertheless, Ice crystal artifacts formed during the tissue freezing process and its inevitably damage to the tissue morphology, causes difficulties in pathological...

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Intra-operative Frozen-Section-pathology diagnostic IHC Products -CELNOVTE-3

Catalog Name Mmab Rmab Mmab Rmab Mmab Mmab Mmab Mmab Mmab Mmab Mmab Mmab Clinic significance Mmab Mmab Mmab Mmab Rmab Mmab Mmab - Rapid detection of tumor markers, reduce misdiagnosis from sole H&E examinations. - Accurate diagnosis of challenging cases, such as metastatic microlesions and infiltrative microlesions. Reduce the false negative rate. - Improve the match rate with post-operative FFPE IHC results. - Assist in better surgical decision. Mmab Mmab Mmab Mmab Mmab Mmab Mmab Mmab Mmab

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Intra-operative Frozen-Section-pathology diagnostic IHC Products -CELNOVTE-4

RTU primary antibodies Panels of specialized ready-to-use primary antibodies are provided for frozen section IHC applications. Proprietary fixative Our specially designed fixative provides crisp morphology enabling remarkable consistency between the frozen section IHC results and the post-operational FFPE IHC results. CORE ADVANTAGES Proprietary wash buffer Our proprietary wash buffer formulation induces shorter wash cycles and cleaner background. 2-step amplification system Compare to competitor’s 1-step detection method which utilizes Poly-HRP labeled primary antibody, our 2-step method is far...

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