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Xpert® EV

Xpert® EV

Xpert® EV

Product catalog summary
Introduction
Xpert® EV is a rapid molecular in vitro diagnostic test designed to detect enteroviral meningitis. It offers a faster alternative to traditional methods, aiding in the swift differentiation between viral and bacterial meningitis, which is crucial for effective treatment.

The Need
Enteroviral (EV) meningitis is prevalent among young children and often presents similarly to bacterial meningitis, making differentiation challenging. Annually, Europe sees an estimated 28,000 to 43,000 cases of EV meningitis, which is typically self-limiting and does not require antibiotics. However, due to diagnostic challenges, patients are often treated empirically, leading to unnecessary hospital costs.

The Solution
Xpert® EV provides rapid and accurate detection of enterovirus from CSF specimens in approximately 2.5 hours. This allows for appropriate patient management, reducing the need for empirical treatment and providing reassurance to patients and families.

Performance
The test demonstrates high sensitivity (96.3% to 100%) and specificity (97% to 97.2%), ensuring reliable results. It covers a comprehensive range of significant serotypes, aiding in accurate diagnosis.

Workflow
The process involves six simple steps with a total hands-on time of less than five minutes. Results are available in less than 2.5 hours, facilitating optimal patient management decisions.

Ordering Information
Xpert® EV is available in packs of 10 cartridges with reagents, catalog number GXev-100n-10.

Contact Information
For direct sales, contact offices in the UK, France, and Benelux. Corporate headquarters are located in Sunnyvale, CA, USA, with European headquarters in Maurens-Scopont, France.
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Catalog excerpts

Xpert® EV-1

The only rapid molecular in vitro diagnostic Enteroviral meningitis test. In Vitro Diagnostic Medical Device

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Xpert® EV-2

“Knowing whether the meningitis is viral or bacterial is imperative to early effective treatment. Because Xpert® EV is significantly faster than existing methods for diagnosing meningitis, it could minimize delays in treating patients. Swift recognition of the cause and appropriate treatment is critical to patient recovery.” Adopted from FDA News, P07-46, March 16, 2007 Sensitive and Specific Provide the best patient management decisions. Table 1B: Banked prospectively collected clinical samples evaluated against “Clinical Diagnosis” Table 1A: Prospective clinical samples evaluated against “Clinical...

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Xpert® EV-3

Xpert® EV • Fully automated process reduces handling time to just minutes • Random access for flexibility and workflow optimization • apid results to improve patient management R • ully integrated reagent and instrument system for accuracy and reproducibility F Total hands-on time: <5 Minutes Dispense Binding Reagent into Port 1 Dispense Wash Reagent into Port 2 Dispense Elution Reagent into Port 3 Add 140µl of Lysis Reagent into Port 4S Add 140µl of Sample into Port 4S Insert cartridge and start assay ORDERING INFORMATION Xpert® EV (10 cartridges with reagents) . . . . . . . . . . . . . . ....

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.