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Xpert® MRSA/SA SSTI

Xpert® MRSA/SA SSTI

Xpert® MRSA/SA SSTI

Product catalog summary
Introduction
The document discusses the Xpert® MRSA/SA SSTI test, a rapid diagnostic tool for detecting Methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus (SA) in skin and soft tissue infections (SSTIs) within one hour.

The Need
SSTIs are a significant health concern, with Staphylococcus aureus being the most common cause. MRSA accounts for over 50% of these infections in parts of the U.S. Traditional laboratory methods can take up to 72 hours to identify MRSA or SA, leading to incorrect empiric treatment in 57% of cases.

The Solution
The Xpert® MRSA/SA SSTI test offers a rapid, on-demand solution for detecting MRSA and SA from swabs in less than an hour. It is comprehensive, targeting Staph aureus, MRSA, and mecA, and identifies presumptive positive strains for accurate classification. The test is automated using the GeneXpert® System, reducing hands-on time and improving laboratory efficiency.

Healthcare Benefits
Rapid detection ensures timely therapy, improves patient management, enables targeted antimicrobial therapy, and allows immediate infection identification for better isolation and infection control.

Performance
The test shows a positive percent agreement of 93.8% for MRSA and 95.7% for SA, with negative percent agreements of 97.3% and 89.5%, respectively. It was validated in a multi-site study comparing it to enriched culture methods.

Workflow
The process involves three simple steps with a total hands-on time of two minutes: inserting the swab into the sample reagent vial, vortexing and dispensing the sample into port S, and inserting the cartridge to start the assay.

Ordering Information
The product is available as a set of 10 cartridges with reagents, under catalog number GXMRSA/SA-SSTI-10.

Contact Information
Corporate headquarters are located in Sunnyvale, CA, USA, with contact details provided for both the U.S. and European offices.
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Catalog excerpts

Xpert® MRSA/SA SSTI-1

Xpert MRSA/SA SSTI ® Xpert MRSA/SA SSTI ® Detect MRSA & SA Skin and Soft Tissue Infections In Less Than One Hour

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Xpert® MRSA/SA SSTI-2

“MRSA is the most common identifiable cause of skin and soft-tissue infection among patients presenting to emergency departments. When antimicrobial therapy is indicated for the treatment of skin and softtissue infections, clinicians should consider obtaining cultures and modifying empirical therapy to provide MRSA coverage.” Moran, et al. New England Journal of Medicine, August 2006 SSTIs are a major health concern: The only rapid and comprehensive SSTI test available: • he most common cause of skin and soft tissue T infections is Staph aureus; MRSA represents over 50% of these infections in...

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Xpert® MRSA/SA SSTI-3

Performance Performance characteristics of Xpert® MRSA/SA SSTI were determined in a multi-site prospective investigation study at three institutions by comparing the Xpert MRSA/SA SSTI test on the GeneXpert® System to enriched culture, the most sensitive culture method. SUMMARY OF RESULTS Positive Percent Agreement Negative Percent Agreement MRSA/SA Performance in Subjects with No Antibiotic Use (within 3 weeks of sample collection) vs. Reference Culture Culture MRSA+ Neg/No Growth MRSA+ Xpert 1 of the 137 were mixed infections of MRSA and SA. 2 of the 3 were mixed infections of MRSA and SA....

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Xpert® MRSA/SA SSTI-4

Xpert® MRSA/SA SSTI • apid results to improve patient management R • ully integrated reagent and instrument system for accuracy and reproducibility F • Random access for flexibility and workflow optimization • Fully automated process reduces handling time to just minutes Total hands-on time: 2 Minutes Insert swab into Sample Reagent vial and break Vortex and dispense Sample into Port S Insert Cartridge and start assay ORDERING INFORMATION Xpert® MRSA/SA SSTI (10 cartridges with reagents) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Catalog No. GXMRSA/SA-SSTI-10...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.