Xpert MTB/RIF Ultra ® Raising the Standard for Tuberculosis Diagnosis Xpert MTB/RIF Ultra ® Active Case Finding for TB Elimination In Vitro Diagnostic Medical Device May not be available in all countries.

With Xpert® MTB/RIF Ultra as frontline diagnosis we are moving a step closer towards TB elimination. It’s a game changer for overcoming the challenge of fast diagnosis of TB in smear-negative patients.” Daniela Maria Cirillo, M.D., Ph.D. WHO collaborating Centre and TB Supranational Reference Laboratory San Raffaele Scientific Institute, Italy In 2015, 10.4 million people developed active tuberculosis (TB) (11% of which were HIV positive) and 1.4 million people lost their lives to the disease.1 Enhancing the Standard Xpert® MTB/RIF revolutionized the management of Mycobacterium tuberculosis (MTB)...

THE IMPACT Preventing the transmission of MTB by fast identification of contagious patients, placing them in airborne infection isolation and initiating the right antibiotic therapy as soon as possible are crucial to ‘END TB’. Recently published recommendations by global experts demonstrate the efficiency of using Xpert® MTB/RIF Ultra as a frontline test over smear microscopy or line probe assays followed by culture-based methods for drug susceptibility testing.7,8,9 Thus, a single modification of the diagnostic algorithm to detect smear-positive and smear-negative TB patients improves active...

Total hands-on time: <1 minute System Throughput* Number of tests per 8-hour shift 560 Add Sample Reagent to sample tube and incubate for 15 minutes at room temperature * Assume 15% MTB positivity rate and average TTR of 66.8 min per test. Actual throughput may vary based on the local prevalence. Insert cartridge and start test sample into cartridge Xpert® MTB/RIF Ultra is a semi-quantitative, nested real-time PCR in vitro diagnostic test for the detection of Mycobacterium tuberculosis (MTB) complex DNA and rifampin-resistance associated mutations of the rpoB gene. CATALOG INFORMATION Xpert MTB/RIF...