CHROMagar™ C3GR

Product catalog summary

Overview: CHROMagar™ C3GR is a specialized medium designed for the overnight detection of Gram-negative bacteria that produce Beta-Lactamase, particularly those with reduced susceptibility to third-generation cephalosporins. This medium is notable for its fast results, species differentiation, high sensitivity, and efficiency in terms of time and workload savings.

Key Features:

Fast Results: Detection is possible after overnight incubation.
Species Differentiation: Utilizes chromogenic performance to differentiate species, including E. coli, Klebsiella, Enterobacter, Citrobacter, Proteus, Pseudomonas, and Acinetobacter.
High Sensitivity: Does not inhibit plasmid-mediated AmpC-producing bacteria.
Time and Workload Savings: Allows direct culture from specimens without the need for selective pre-enrichment.

Background: The production of β-Lactamase is a common mechanism of drug resistance in Gram-negative bacteria. Rapid detection is crucial for infection control and targeted therapy, conserving carbapenem antibiotics for severe infections.

Product Specifications:

Powder Base: Contains agar, peptone, yeast extract, and chromogenic mix.
Storage: Powder base stored at 15/30°C, supplement at 2/8°C. Both have a shelf life of 2 years.
Procedure: Direct streaking with incubation for 18-24 hours at 37°C under aerobic conditions.

Quality Control Strains: Includes E. coli CTXM CIP10392, E. cloacae ATCC® 35030, and others, with specific colony colorations and inhibition details.

Ordering Information: Available in 5000 ml and 25 L packs, with bulk options on request. Product references include CGRT2 and CGRT3-25.

Manufacturer: CHROMagar, based in Paris, France. Contact information and distributor details are available on their website.

Catalog excerpts

Clinical Microbiology C.krusei C.albicans For overnight detection of Gram-negative bacteria producing Beta-Lactamase

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For overnight detection of Gram-negative bacteria producing Beta-Lactamase Background β-Lactamase production (ESBL, AmpC,...) is the most common mechanism of β-lactam drug resistance in gram-negative bacteria. Many clinical laboratories currently screen for ESBLs but do not screen for AmpC β-lactamases; though bacteria (mostly Klebsiella pneumonia, E. coli, Enterobacter and Proteus) producing plasmid-mediated AmpC β-lactamases have been responsible for nosocomial outbreaks. Therefore, it is crucial to ensure that proper surveillance is in place to help establish appropriate guidelines and policies...

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All CHROMagar catalogs and technical brochures

*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.

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