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MONOCYTES-R

MONOCYTES-R

MONOCYTES-R

Product catalog summary
Overview of Mononuclear Cells from Peripheral Blood
Monocytes and lymphocytes are large white blood cells, comprising 1% to 6% of the cellular population in the bloodstream. They originate from hematopoietic stem cells in the bone marrow and have several key functions:
  • Monocytes ingest and destroy pathogens, foreign particles, and cellular debris, initiating immune responses.
  • Once differentiated into macrophages, they enhance functionality and promote new blood vessel formation.
  • They release signaling molecules that modulate inflammation and trigger tissue regeneration.
Indications for Use – Monocytes-R
Monocytes-R is indicated for various medical conditions, including:
  • Musculoskeletal disorders: tendinopathies, tendon and ligament injuries, arthritis, and cartilage lesions.
  • Spinal surgery: early-stage discopathies and stenosis, low back and cervical pain.
  • Coloproctology: Crohn’s disease.
  • Gynecology: infertility and tissue regeneration support.
  • Urology: erectile dysfunction.
  • Complex wound management: diabetic foot, ischemic limb, ulcers, and wounds.
  • Aesthetic medicine: tissue regeneration for aging-related damage.
  • Plastic surgery: scar recovery and deep tissue regeneration.
  • Trichology: early-stage androgenetic alopecia and post-transplant graft promotion.
Procedure and Device Description
Monocytes-R is a closed-circuit device that retrieves mononuclear cells and growth factors from peripheral blood without centrifugation, minimizing cellular stress and contamination risk. The process results in a cellular concentrate with three times the initial cell count and a significant reduction in pro-inflammatory granulocytes.
Technique
  1. Collection: Assemble the kit in a sterile field, load syringes with anticoagulant, and draw 120 ml of blood using a dedicated needle.
  2. Processing: Hang the kit, introduce blood into the upper bag, activate the filter circuit, and allow blood to clear the filter, depositing waste in the lower bag.
  3. Recovery: Close clamps, open the side clamp, inject sterile saline, and retrieve the content from the collection bag.
Contact Information
Clover Orthopedics s.r.l.
Phone: +39 02 457 902 31
Email: [email protected]
Website: cloverorthopedics.com
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Catalog excerpts

MONOCYTES-R-2

• Musculoskeletal disorders: tendinopathies, tendon and ligament injuries; symptomatic treatment of inflammatory joint disorders (arthritis) and cartilage lesions, also in association with hyaluronic acid. • Spinal surgery: discopathies and lumbar and cervical stenosis in the early stage, low back pain and cervical pain. • Coloproctology: Crohn's disease. • Gynecology: infertility and support of tissue regeneration processes. • Urology: erectile dysfunction. • Management of complex wounds: diabetic foot, ischemic limb, ulcers and wounds, with support of tissue regeneration processes. • Aesthetic...

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MONOCYTES-R-3

DIFFERENCE BETWEEN MONONUCLEAR CELLS AND PLATELETS Platelets are small anucleated cells present in the blood that, through the release of growth factors and cytokines, help reduce inflammatory processes and stimulate tissue regeneration. EFFECTIVE, FAST AND SAFE PROCEDURE Monocytes-R is the only closed-circuit device that enables the retrieval of mononuclear cells and growth factors from peripheral blood in a fast, reproducible manner and without the need for centrifugation. This minimizes cellular stress, reduces the risk of contamination, and allows the procedure to be performed simply and...

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MONOCYTES-R-4

TECHNIQUE 1 - Collection Open the kit in the sterile field and assemble it as illustrated. Load the collection syringes with 10% anticoagulant (ACD-A): that is, 6 ml for every 60 ml of blood. The recommended collection volume is 120 ml. Clean the collection site and, using the dedicated cannula needle, draw the required volume of peripheral blood. 2 – Processing Hang the kit on an IV stand, keeping the upper bag (A) elevated. Introduce the collected blood through the upper connector (a) to fill bag (A), and activate the filter circuit by opening the designated clamps (1 and 2). Wait until all...

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MONOCYTES-R-5

<• CLOVER NEXTClover Orthopedics s.r.l. M. [email protected] SISTEMA Dl GESTIONE QUALITA CERTIFICATO

 Open the catalog to page 5

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.
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