why bicompartmental A REVOLUTIONARY ALTERNATIVE TO TOTAL KNEE REPLACEMENTS
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L edingham J., et al; Radiographic Patterns and Associations of Osteoarthritis of the Knee in Patients Referred to Hospital; Ann Rheum Dis; Jul 1993; Vol. 52(7): pp. 520-526; PMID: 8346979 R olston L, et al.; Bicompartmental knee arthroplasty: a bone-sparing, ligamentsparing and minimally invasive alternative for active patients; Orthopedics; Aug 2007; Vol. 30(8):pp. 70-73; PMID: 17824339 N oble P., et al.; The John Insall Award: Patient expectations affect satisfaction with total knee arthroplasty; Clin Orthop Relat Res; Nov 2006; Vol. 452: pp. 35–43; PMID: 16967035 B ourne R., et al.; Patient satisfaction after total knee arthroplasty: Who is satisfied and who is not; Clin Orthop Relat Res; Jan 2010; Vol. 468(1): pp. 57-63; PMID: 19844772 S uda A.; Are patients’ expectations of hip and knee arthroplasty fulfilled? A prospective study of 130 patients; Orthopedics; Feb 2010; Vol. 33(2): pp. 76-60; PMID: 20192137 R iddle D, et al.; Yearly Incidence of Unicompartmental Knee Arthroplasty in the United States, Journal of Arthroplasty; Apr 2008; Vol. 23(3): pp. 408-412; PMID: 18358380 P ap G, et al.; Detailed analysis of proprioception in normal and ACL-deficient knees; J Bone Joint Surg Br; Sep 1999; Vol. 81(5): pp. 764-768; PMID: 10530833 C arter N, et al.; Joint position sense and rehabilitation in the anterior cruciate ligament deficient knee; Br J Sports Med; Sep 1997; Vol. 31(3): pp. 209-212; PMID: 9298555 D alury D., et al.; Unicompartmental knee arthroplasty compares favorably to total knee arthroplasty in the same patient; Orthopedics; Apr 2009; Vol. 32(4): pp. 253; PMID: 19388619 L aurencin C; Unicompartmental versus total knee arthroplasty in the same patient: A comparative study; Clin Orthop Relat Res; Dec 1991; Vol. 273: pp. 151-156; PMID: 1959264 R ougraff B, et al.; A comparison of tricompartmental and unicompartmental arthroplasty for the treatment of gonarthrosis; Clin Orthop Relat Res; Dec 1991; Vol. 273: pp. 157–164; PMID: 1959265 P atil S, et al.; Can normal knee kinematics be restored with unicompartmental knee replacement?; J Bone Joint Surg AM; Feb 2005; Vol. 87(2): pp. 332-338; PMID: 15687156 L astad-Lygre S., Pain and function in patients after primary unicompartmental and total knee arthroplasty; J Bone Joint Surg Am; Dec 2010; Vol. 92(18): pp. 2890-2897; PMID: 21159989 N ewman JH, et al.; Unicompartmental or total knee replacement? 15 year results of a prospective, randomized controlled trial; J Bone Joint Surg Br; Jan 2009; Vol. 91B(1): pp. 52-57; DOI:10.1302/0301-620X.91B1.20899 B erger RA, et al.; Results of Unicompartmental Knee Arthroplasty at a Minimum of Ten Years of Follow-up; J Bone Joint Surg Am; May 2005; Vol. 87(5): pp. 999-1006; PMID: 15866962 bicompartmental? A REVOLUTIONARY ALTERNATIVE TO TOTAL KNEE REPLACEMENTS ConforMIS, Inc. 11 North Avenue • Burlington, MA 01803 • Phone: 781.345.9001 • Fax: 781.345.0147 Authorized Representative: Medical Device Safety Service, GMBH • Schiffgraben 41, 30175 Hannover, Germany • P: +49 (511) 6262.8630 • F: +49 (511) 6262.86333 Copyright © by ConforMIS, Inc. All rights reserved. iDuo and ConforMIS are registered trademarks of ConforMIS. CAUTION: Federal law (USA) restricts this device to sale by or on the order of a physician. The ConforMIS iDuo G2 is intended for use only by physicians trained in the proper use of the device and accompanying instrumentation.

Today, many patients ^WT1IX\A I I I I I with medial or lateral involvement receive a Total without consideration

TKR is not always needed Osteoarthritis (OA) disease pattern studies have shown that bicompartmental disease is the most common disease pattern found amongst knee OA patients. • edingham J., et al., demonstrated through radiographic L examination of 252 patients (470 knees) with OA of the knee that 58% of the knees were affected with bicompartmental OA; 50% in the medial compartment / PF joint and 8% in the lateral compartment / PF joint 1 • Rolston L., et al., tracked 100 patients older than 40 years of age, and identified through radiographic interpretation that 73% had involvement of...

As patients become more demanding and more active, the interest in bone and tissue sparing Partial Knee Replacement (PKR) approaches has increased dramatically. PKR More surgeons recommending PKR Recent data indicates surgeons are recommending PKR to their patients more and more frequently. • iddle, et al., in a 2008 study measuring the R incidence of PKR in the United States over an 8 year period, reported that PKR procedures grew at 3 times the rate of TKR procedures7 PKR procedures have been growing 3 times the rate of TKR procedures A less invasive option In studies measuring the role...

Higher patient satisfaction and better outcomes In comparative studies of patients with both PKR and TKR implants, patients have reported better early flexion, higher range of motion and a more natural feel of the PKR implant. • Dalury DF, et al., in a 2009 study of 23 bilateral patients receiving PKR implants in one knee and a TKR implant in the other knee, identified that more than 50% of patients preferred their PKR implant to their TKR implant while none preferred their TKR to their PKR implant 10 • Laurencin, CT, in a comparative study of 23 patients with PKR implants in one knee and...

to bicompartmental patients A revolutionary alternative The iDuo® G2 bicompartmental knee resurfacing system offers a revolutionary alternative to traditional TKR by combining proven TKA principles for patellofemoral treatment with the advantages of the ConforMIS partial knee system. With the iDuo G2, a surgeon can treat just the affected compartments with a precise, patient specific implant that delivers unparalleled fit, preserves all ligaments and conserves far more bone than traditional TKA. Not only does this provide patients with a more natural knee motion, it also preserves future...

L edingham J., et al; Radiographic Patterns and Associations of Osteoarthritis of the Knee in Patients Referred to Hospital; Ann Rheum Dis; Jul 1993; Vol. 52(7): pp. 520-526; PMID: 8346979 R olston L, et al.; Bicompartmental knee arthroplasty: a bone-sparing, ligamentsparing and minimally invasive alternative for active patients; Orthopedics; Aug 2007; Vol. 30(8):pp. 70-73; PMID: 17824339 N oble P., et al.; The John Insall Award: Patient expectations affect satisfaction with total knee arthroplasty; Clin Orthop Relat Res; Nov 2006; Vol. 452: pp. 35–43; PMID: 16967035 B ourne R., et al.;...