Benchtop Environmental Chamber 2024 Edition

OINDP Testing Variability and Environmental Conditions Many factors have been identified that could give rise to variability in the testing of orally inhaled and nasal drug products (OINDPs). Each of these factors reduces the discriminatory power of tests to accurately determine product variability. Effective strategies to mitigate sources of variability in delivered dose uniformity (DDU) testing and aerodynamic particle size distribution (APSD) measurement have been the focus of rigorous investigation for many years. Environmental conditions is one key area.

Localised changes in laboratory temperature and humidity, and also the presence of electrostatic charge, are known to have a direct influence on the dose emission and aerosol generation performance of OINDPs, thereby compromising DDU and APSD test data integrity. • Particle/droplet evaporation effects for MDIs, nebulisers, ADIs, nasal sprays and aerosols • Accuracy of volumetric air flow rate measurements during testing • Particle/droplet evaporation effects for MDIs, nebulisers, ADIs, nasal sprays and aerosols • Water absorption effects for hygroscopic powder-based DPI formulations • Electrostatic...

Inhaler Testing EnviroMate Inadequate control of environmental conditions can affect the dose emission and aerosol generation performance of OINDPs, leading to erroneous data and costly testing delays. EnviroMate is a cost-effective, compact, benchtop solution that addresses these issues with considerable value for scientists faced with: • variable laboratory conditions or inadequate climate control • OINDPs with high sensitivity to temperature, humidity and/or electrostatic charge • poor reproducibility and unexplained out-of-specification (OOS) results • achieving better environmental control,...

Key Features: Sensitive temperature and relative humidity sensor ensures accurate performance Adjacent holder for BAC 100i/ TPK 100i Temperature and Relative Humidity Sensor included Anti-static system minimises electrostaticinduced variability Internal light maximises visibility Easy-to-remove water supply/waste reservoirs Temperature and relative humidity parameters are easily set and clearly visible to users Large, slot-sealed entry ports enable easy handling of test equipment A large, hinged door provides easy access Access ports and built-in quick-release connectors accommodate a wide range...

Inhaler Testing Read the Full Application Note EnviroMate™ Performance Data EnviroMate has been specifically designed to accommodate a wide range of inhaler testing apparatus, including: • Next Generation Impactor (NGI) and Glass Twin Impinger (GTI) Heat & Dehumidify • Inhaler Testing Workstation™ ITW with DUSA for MDIs and DPIs, Waste Shot Collector WSC2, Andersen Cascade Impactor (ACI) and Multi-Stage Liquid Impinger (MSLI) EnviroMate Performance Envelope Heat & Humidify EnviroMate can also interface with the BRS 200i and NGI Cooler™ for nebuliser testing, and flow controllers and vacuum pumps...

EnviroMate with Next EnviroMate with Inhaler Testing EnviroMate with Andersen Generation Impactor (NGI) Workstation™ ITW and DUSA for DPIs Cascade Impactor (ACI) EnviroMate with Breathing Simulator BRS 200i for nebuliser testing EnviroMate™Cat. No. Description 5040 EnviroMate™ Environmental Chamber 5042 IQ/OQ Documentation for EnviroMate™ 5043 Qualification Tools for EnviroMate™ 5044 Recalibration of EnviroMate™ Qualification Tools

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