Impactor Coater™ IC 200i Impaction surface coater for both NGI Collection Cups and ACI Collection Plates IC 200i with NGI Collection Cup Tray IC 200i with ACI Collection Plate Tray & Cups ACI Collection Plate Tray & Cups purchased separately. (Cat. No. 5933) To prevent particle bounce and subsequent re-entrainment within the flowing airstream during aerodynamic particle size distribution (APSD) sampling, the pharmacopoeias recommend the coating of each impactor stage collection surface. However, the manual coating of each collection surface is prone to variability and is labour-intensive. The Impactor Coater IC 200i reproducibly applies surface coatings to both the NGI Collection Cups and the ACI Collection Plates, eliminating the problem of particle bounce and re-entrainment when using cascade impactors to measure the APSD of OINDPs. Coats surfaces in as little as 2 minutes Standardising the application of surface coating to each collection surface, the IC 200i removes the inherent variability associated with the coating process, while boosting laboratory productivity and throughput. A note about impaction surface coating Frees up analysts for other tasks For OINDPs where the particles are hard and dry, (e.g. Dry Powder Inhalers (DPIs)) or where only a few actuations are delivered to the impactor, such as is the case for Metered Dose Inhaler (MDIs), particle bounce and re-entrainment in the flowing airstream can bias the measured size data to finer sizes. Enables easy method transfer between sites It is therefore important to assess the potential impact of these phenomena on downstream stages at an early point in development so that corrective action can be taken. Minimises coating solution wastage Coating the impaction surfaces with a tacky, viscous material such as glycerol or silicone oil is recommended by the regulators to address this problem. If a surface coating is required, the amount, its uniformity and the method in which it is applied and its potential to affect drug recovery should be assessed during method development.

Precisely dispenses excess fluid to ensure complete collection surfaces coating. The reverse cycle empties out any excess back into the reservoir for future use, leaving a thin and consistent coating behind. Compatible with a wide range of coating solutions Dedicated channel per cup/plate Intuitive touchscreen interface simplifies operation Extensive data output options Setting flow rate Setting dispense time Qualification & Maintenance Dispense Rate • Comprehensive IQ/OQ/PQ documentation Dispense and Reverse Cycle Time package and toolkit available • Extended warranty available Impactor Coater...